The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q969F1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006351 transcription, DNA-templated GO:0006383 transcription from RNA polymerase III promoter GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter GO:0042797 tRNA transcription from RNA polymerase III promoter
AF361496 - Homo sapiens NPD020 mRNA, complete cds. AF361492 - Homo sapiens CDA020 mRNA, complete cds. BC104655 - Homo sapiens general transcription factor IIIC, polypeptide 6, alpha 35kDa, mRNA (cDNA clone IMAGE:6739343), partial cds. BC011593 - Homo sapiens general transcription factor IIIC, polypeptide 6, alpha 35kDa, mRNA (cDNA clone MGC:20479 IMAGE:4639268), complete cds. AK057977 - Homo sapiens cDNA FLJ25248 fis, clone STM03469. KJ899979 - Synthetic construct Homo sapiens clone ccsbBroadEn_09373 GTF3C6 gene, encodes complete protein. EF137904 - Homo sapiens TFIIIC35 mRNA, complete cds.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q969F1 (Reactome details) participates in the following event(s):
R-HSA-76054 Binding of TFIIIC to TFIIIA:Type I Promoter complex R-HSA-83788 Binding of TFIIIC to Type 2 promoter R-HSA-83723 Binding of TFIIIB to TFIIIC:TFIIIA:Type I Promoter complex R-HSA-83790 Binding of TFIIIB to TFIIC: Type 2 Promoter Complex R-HSA-112055 RNA Polymerase III Abortive Initiation At Type 1 Open Promoters R-HSA-112153 RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters R-HSA-76060 RNA Polymerase III Promoter Opening at Type 1 Promoters R-HSA-112149 RNA Polymerase III Abortive Initiation At Type 2 Open Promoters R-HSA-112155 RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters R-HSA-112150 RNA Polymerase III Promoter Opening at Type 2 Promoters R-HSA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex R-HSA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation R-HSA-76046 RNA Polymerase III Transcription Initiation R-HSA-74158 RNA Polymerase III Transcription R-HSA-74160 Gene expression (Transcription)
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
