ID:GTPB1_HUMAN DESCRIPTION: RecName: Full=GTP-binding protein 1; Short=G-protein 1; Short=GP-1; Short=GP1; FUNCTION: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity). SUBUNIT: Interacts with EXOSC2/RRP4, EXOSC3/RRP40, EXOSC5/RRP46, HNRNPD, HNRNPR and SYNCRIP. Identified in a complex with AANAT mRNA, but does not bind mRNA by itself (By similarity). SUBCELLULAR LOCATION: Cytoplasm (By similarity). SIMILARITY: Belongs to the GTPBP1 GTP-binding protein family. SEQUENCE CAUTION: Sequence=AAB51273.1; Type=Erroneous initiation; Sequence=CAG30387.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O00178
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006955 immune response GO:0007165 signal transduction GO:0046039 GTP metabolic process GO:0061014 positive regulation of mRNA catabolic process
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
