The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6FH11
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0001525 angiogenesis GO:0001666 response to hypoxia GO:0006788 heme oxidation GO:0006979 response to oxidative stress GO:0007264 small GTPase mediated signal transduction GO:0008217 regulation of blood pressure GO:0008219 cell death GO:0008285 negative regulation of cell proliferation GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage GO:0010656 negative regulation of muscle cell apoptotic process GO:0016239 positive regulation of macroautophagy GO:0016242 negative regulation of macroautophagy GO:0031670 cellular response to nutrient GO:0032764 negative regulation of mast cell cytokine production GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron GO:0035556 intracellular signal transduction GO:0042167 heme catabolic process GO:0042168 heme metabolic process GO:0042542 response to hydrogen peroxide GO:0043065 positive regulation of apoptotic process GO:0043305 negative regulation of mast cell degranulation GO:0043392 negative regulation of DNA binding GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity GO:0043524 negative regulation of neuron apoptotic process GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043627 response to estrogen GO:0045766 positive regulation of angiogenesis GO:0048662 negative regulation of smooth muscle cell proliferation GO:0051090 regulation of sequence-specific DNA binding transcription factor activity GO:0055114 oxidation-reduction process GO:0071243 cellular response to arsenic-containing substance GO:0071276 cellular response to cadmium ion GO:0072719 cellular response to cisplatin GO:0097421 liver regeneration GO:1904036 negative regulation of epithelial cell apoptotic process GO:1904706 negative regulation of vascular smooth muscle cell proliferation