ID:HYI_HUMAN DESCRIPTION: RecName: Full=Putative hydroxypyruvate isomerase; EC=5.3.1.22; AltName: Full=Endothelial cell apoptosis protein E-CE1; FUNCTION: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity). CATALYTIC ACTIVITY: Hydroxypyruvate = 2-hydroxy-3-oxopropanoate. INDUCTION: Up-regulated by exposure to 7,8-Dihydroxy-9,10-epoxy- 7,8,9,10-tetrahydrobenzo[a]pyrene (BPDE) after which is found in the culture medium of amniotic epithelial cells. SIMILARITY: Belongs to the hyi family. SEQUENCE CAUTION: Sequence=AAH06140.1; Type=Frameshift; Positions=271; Sequence=AAH19041.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAV84474.1; Type=Frameshift; Positions=215, 228, 232, 238;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q5T013
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
