Human Gene ITGAV (ENST00000261023.8_7) from GENCODE V47lift37
  Description: integrin subunit alpha V, transcript variant 1 (from RefSeq NM_002210.5)
Gencode Transcript: ENST00000261023.8_7
Gencode Gene: ENSG00000138448.13_14
Transcript (Including UTRs)
   Position: hg19 chr2:187,454,783-187,545,628 Size: 90,846 Total Exon Count: 30 Strand: +
Coding Region
   Position: hg19 chr2:187,455,066-187,542,019 Size: 86,954 Coding Exon Count: 30 

Page IndexSequence and LinksUniProtKB CommentsPrimersMalaCardsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsPathwaysOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr2:187,454,783-187,545,628)mRNA (may differ from genome)Protein (1048 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedReactome
UniProtKBWikipediaBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: ITAV_HUMAN
DESCRIPTION: RecName: Full=Integrin alpha-V; AltName: Full=Vitronectin receptor subunit alpha; AltName: CD_antigen=CD51; Contains: RecName: Full=Integrin alpha-V heavy chain; Contains: RecName: Full=Integrin alpha-V light chain; Flags: Precursor;
FUNCTION: The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
SUBUNIT: Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8 subunit. Interacts with HIV-1 Tat. Alpha- V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus (By similarity). Alpha- V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses. Interacts with RAB25.
INTERACTION: P05106:ITGB3; NbExp=9; IntAct=EBI-298282, EBI-702847; P18084:ITGB5; NbExp=2; IntAct=EBI-298282, EBI-1223434;
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
SIMILARITY: Belongs to the integrin alpha chain family.
SIMILARITY: Contains 7 FG-GAP repeats.
SEQUENCE CAUTION: Sequence=BAD93131.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: ITGAV
Diseases sorted by gene-association score: west nile virus (16), pharyngoconjunctival fever (11), fibrolamellar carcinoma (9), cerebral hypoxia (9), priapism (9), insulin-like growth factor i (9), colon carcinoma in situ (7), retinitis pigmentosa 42 (7), mouth disease (6), herpes simplex (6), hiv-1 (2), colorectal cancer (1)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 33.47 RPKM in Artery - Aorta
Total median expression: 733.90 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -149.10283-0.527 Picture PostScript Text
3' UTR -757.503609-0.210 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR013517 - FG-GAP
IPR013519 - Int_alpha_beta-p
IPR000413 - Integrin_alpha
IPR013649 - Integrin_alpha-2
IPR018184 - Integrin_alpha_C_CS

Pfam Domains:
PF00357 - Integrin alpha cytoplasmic region
PF01839 - FG-GAP repeat
PF08441 - Integrin alpha

SCOP Domains:
69179 - Integrin domains
69318 - Integrin alpha N-terminal domain

Protein Data Bank (PDB) 3-D Structure
MuPIT help
1JV2 - X-ray MuPIT 1L5G - X-ray MuPIT 1M1X - X-ray MuPIT 1U8C - X-ray MuPIT 3IJE - X-ray MuPIT


ModBase Predicted Comparative 3D Structure on P06756
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0001618 virus receptor activity
GO:0001846 opsonin binding
GO:0001968 fibronectin binding
GO:0002020 protease binding
GO:0005080 protein kinase C binding
GO:0005102 receptor binding
GO:0005178 integrin binding
GO:0005245 voltage-gated calcium channel activity
GO:0005515 protein binding
GO:0015026 coreceptor activity
GO:0042277 peptide binding
GO:0046872 metal ion binding
GO:0050431 transforming growth factor beta binding
GO:0050840 extracellular matrix binding
GO:1990430 extracellular matrix protein binding
GO:0017134 fibroblast growth factor binding
GO:0019960 C-X3-C chemokine binding
GO:0031994 insulin-like growth factor I binding
GO:0038132 neuregulin binding

Biological Process:
GO:0001525 angiogenesis
GO:0001568 blood vessel development
GO:0001570 vasculogenesis
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0006874 cellular calcium ion homeostasis
GO:0007155 cell adhesion
GO:0007160 cell-matrix adhesion
GO:0007204 positive regulation of cytosolic calcium ion concentration
GO:0007229 integrin-mediated signaling pathway
GO:0008284 positive regulation of cell proliferation
GO:0010745 negative regulation of macrophage derived foam cell differentiation
GO:0010888 negative regulation of lipid storage
GO:0016032 viral process
GO:0016477 cell migration
GO:0030198 extracellular matrix organization
GO:0030335 positive regulation of cell migration
GO:0031589 cell-substrate adhesion
GO:0032369 negative regulation of lipid transport
GO:0033627 cell adhesion mediated by integrin
GO:0033690 positive regulation of osteoblast proliferation
GO:0034113 heterotypic cell-cell adhesion
GO:0034446 substrate adhesion-dependent cell spreading
GO:0035987 endodermal cell differentiation
GO:0038027 apolipoprotein A-I-mediated signaling pathway
GO:0038044 transforming growth factor-beta secretion
GO:0043277 apoptotic cell clearance
GO:0043312 neutrophil degranulation
GO:0043410 positive regulation of MAPK cascade
GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process
GO:0045785 positive regulation of cell adhesion
GO:0046718 viral entry into host cell
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0050748 negative regulation of lipoprotein metabolic process
GO:0050764 regulation of phagocytosis
GO:0050900 leukocyte migration
GO:0050919 negative chemotaxis
GO:0052066 entry of symbiont into host cell by promotion of host phagocytosis
GO:0070371 ERK1 and ERK2 cascade
GO:0070588 calcium ion transmembrane transport
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
GO:2000536 negative regulation of entry of bacterium into host cell
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway

Cellular Component:
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005925 focal adhesion
GO:0008305 integrin complex
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0031258 lamellipodium membrane
GO:0031527 filopodium membrane
GO:0031528 microvillus membrane
GO:0032587 ruffle membrane
GO:0034683 integrin alphav-beta3 complex
GO:0034684 integrin alphav-beta5 complex
GO:0034685 integrin alphav-beta6 complex
GO:0034686 integrin alphav-beta8 complex
GO:0035579 specific granule membrane
GO:0035866 alphav-beta3 integrin-PKCalpha complex
GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex
GO:0035868 alphav-beta3 integrin-HMGB1 complex
GO:0045335 phagocytic vesicle
GO:0070062 extracellular exosome


-  Descriptions from all associated GenBank mRNAs
  LF205741 - JP 2014500723-A/13244: Polycomb-Associated Non-Coding RNAs.
LF213852 - JP 2014500723-A/21355: Polycomb-Associated Non-Coding RNAs.
AK309711 - Homo sapiens cDNA, FLJ99752.
AK302550 - Homo sapiens cDNA FLJ57822 complete cds, highly similar to Integrin alpha-V precursor.
AB209894 - Homo sapiens mRNA for integrin alpha-V precursor variant protein.
BC126231 - Homo sapiens integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), mRNA (cDNA clone MGC:161509 IMAGE:8991947), complete cds.
BC136442 - Homo sapiens integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), mRNA (cDNA clone MGC:168054 IMAGE:9020431), complete cds.
BC144100 - Homo sapiens integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), mRNA (cDNA clone MGC:177637 IMAGE:9052620), complete cds.
EF560727 - Homo sapiens clone DKFZp686A08142 ITGAV protein (ITGAV) mRNA, complete cds.
M14648 - Human cell adhesion protein (vitronectin) receptor alpha subunit mRNA, complete cds.
AB527165 - Synthetic construct DNA, clone: pF1KB5610, Homo sapiens ITGAV gene for integrin, alpha V, without stop codon, in Flexi system.
AK302990 - Homo sapiens cDNA FLJ51414 complete cds, highly similar to Integrin alpha-V precursor.
LF347687 - JP 2014500723-A/155190: Polycomb-Associated Non-Coding RNAs.
LF347688 - JP 2014500723-A/155191: Polycomb-Associated Non-Coding RNAs.
LF347689 - JP 2014500723-A/155192: Polycomb-Associated Non-Coding RNAs.
LF347690 - JP 2014500723-A/155193: Polycomb-Associated Non-Coding RNAs.
LF347691 - JP 2014500723-A/155194: Polycomb-Associated Non-Coding RNAs.
LF347692 - JP 2014500723-A/155195: Polycomb-Associated Non-Coding RNAs.
LF347693 - JP 2014500723-A/155196: Polycomb-Associated Non-Coding RNAs.
LF347696 - JP 2014500723-A/155199: Polycomb-Associated Non-Coding RNAs.
LF347697 - JP 2014500723-A/155200: Polycomb-Associated Non-Coding RNAs.
LF347698 - JP 2014500723-A/155201: Polycomb-Associated Non-Coding RNAs.
LF347699 - JP 2014500723-A/155202: Polycomb-Associated Non-Coding RNAs.
LF347700 - JP 2014500723-A/155203: Polycomb-Associated Non-Coding RNAs.
LF347701 - JP 2014500723-A/155204: Polycomb-Associated Non-Coding RNAs.
LF347702 - JP 2014500723-A/155205: Polycomb-Associated Non-Coding RNAs.
LF347704 - JP 2014500723-A/155207: Polycomb-Associated Non-Coding RNAs.
LF347705 - JP 2014500723-A/155208: Polycomb-Associated Non-Coding RNAs.
LF347706 - JP 2014500723-A/155209: Polycomb-Associated Non-Coding RNAs.
BC047454 - Homo sapiens integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), mRNA (cDNA clone IMAGE:5294976).
LF347708 - JP 2014500723-A/155211: Polycomb-Associated Non-Coding RNAs.
LF347709 - JP 2014500723-A/155212: Polycomb-Associated Non-Coding RNAs.
LF347710 - JP 2014500723-A/155213: Polycomb-Associated Non-Coding RNAs.
JD089342 - Sequence 70366 from Patent EP1572962.
JD381082 - Sequence 362106 from Patent EP1572962.
LF347712 - JP 2014500723-A/155215: Polycomb-Associated Non-Coding RNAs.
JD315107 - Sequence 296131 from Patent EP1572962.
JD305055 - Sequence 286079 from Patent EP1572962.
JD503057 - Sequence 484081 from Patent EP1572962.
JD309916 - Sequence 290940 from Patent EP1572962.
JD285145 - Sequence 266169 from Patent EP1572962.
LF347713 - JP 2014500723-A/155216: Polycomb-Associated Non-Coding RNAs.
JD553145 - Sequence 534169 from Patent EP1572962.
JD095572 - Sequence 76596 from Patent EP1572962.
LF347714 - JP 2014500723-A/155217: Polycomb-Associated Non-Coding RNAs.
LF347715 - JP 2014500723-A/155218: Polycomb-Associated Non-Coding RNAs.
JD435096 - Sequence 416120 from Patent EP1572962.
JD168355 - Sequence 149379 from Patent EP1572962.
JD284922 - Sequence 265946 from Patent EP1572962.
JD486212 - Sequence 467236 from Patent EP1572962.
JD534213 - Sequence 515237 from Patent EP1572962.
LF347716 - JP 2014500723-A/155219: Polycomb-Associated Non-Coding RNAs.
JD045825 - Sequence 26849 from Patent EP1572962.
JD130831 - Sequence 111855 from Patent EP1572962.
LF347717 - JP 2014500723-A/155220: Polycomb-Associated Non-Coding RNAs.
JD087210 - Sequence 68234 from Patent EP1572962.
JD557189 - Sequence 538213 from Patent EP1572962.
LF347718 - JP 2014500723-A/155221: Polycomb-Associated Non-Coding RNAs.
LF347719 - JP 2014500723-A/155222: Polycomb-Associated Non-Coding RNAs.
JD298711 - Sequence 279735 from Patent EP1572962.
LF347720 - JP 2014500723-A/155223: Polycomb-Associated Non-Coding RNAs.
LF347721 - JP 2014500723-A/155224: Polycomb-Associated Non-Coding RNAs.
LF347722 - JP 2014500723-A/155225: Polycomb-Associated Non-Coding RNAs.
BC072686 - Homo sapiens cDNA clone IMAGE:6147239, partial cds.
LF347723 - JP 2014500723-A/155226: Polycomb-Associated Non-Coding RNAs.
LF347724 - JP 2014500723-A/155227: Polycomb-Associated Non-Coding RNAs.
MA583264 - JP 2018138019-A/155190: Polycomb-Associated Non-Coding RNAs.
MA583265 - JP 2018138019-A/155191: Polycomb-Associated Non-Coding RNAs.
MA583266 - JP 2018138019-A/155192: Polycomb-Associated Non-Coding RNAs.
MA583267 - JP 2018138019-A/155193: Polycomb-Associated Non-Coding RNAs.
MA583268 - JP 2018138019-A/155194: Polycomb-Associated Non-Coding RNAs.
MA583269 - JP 2018138019-A/155195: Polycomb-Associated Non-Coding RNAs.
MA583270 - JP 2018138019-A/155196: Polycomb-Associated Non-Coding RNAs.
MA583273 - JP 2018138019-A/155199: Polycomb-Associated Non-Coding RNAs.
MA583274 - JP 2018138019-A/155200: Polycomb-Associated Non-Coding RNAs.
MA583275 - JP 2018138019-A/155201: Polycomb-Associated Non-Coding RNAs.
MA583276 - JP 2018138019-A/155202: Polycomb-Associated Non-Coding RNAs.
MA583277 - JP 2018138019-A/155203: Polycomb-Associated Non-Coding RNAs.
MA583278 - JP 2018138019-A/155204: Polycomb-Associated Non-Coding RNAs.
MA583279 - JP 2018138019-A/155205: Polycomb-Associated Non-Coding RNAs.
MA583281 - JP 2018138019-A/155207: Polycomb-Associated Non-Coding RNAs.
MA583282 - JP 2018138019-A/155208: Polycomb-Associated Non-Coding RNAs.
MA583283 - JP 2018138019-A/155209: Polycomb-Associated Non-Coding RNAs.
MA583285 - JP 2018138019-A/155211: Polycomb-Associated Non-Coding RNAs.
MA583286 - JP 2018138019-A/155212: Polycomb-Associated Non-Coding RNAs.
MA583287 - JP 2018138019-A/155213: Polycomb-Associated Non-Coding RNAs.
MA583289 - JP 2018138019-A/155215: Polycomb-Associated Non-Coding RNAs.
MA583290 - JP 2018138019-A/155216: Polycomb-Associated Non-Coding RNAs.
MA583291 - JP 2018138019-A/155217: Polycomb-Associated Non-Coding RNAs.
MA583292 - JP 2018138019-A/155218: Polycomb-Associated Non-Coding RNAs.
MA583293 - JP 2018138019-A/155219: Polycomb-Associated Non-Coding RNAs.
MA583294 - JP 2018138019-A/155220: Polycomb-Associated Non-Coding RNAs.
MA583295 - JP 2018138019-A/155221: Polycomb-Associated Non-Coding RNAs.
MA583296 - JP 2018138019-A/155222: Polycomb-Associated Non-Coding RNAs.
MA583297 - JP 2018138019-A/155223: Polycomb-Associated Non-Coding RNAs.
MA583298 - JP 2018138019-A/155224: Polycomb-Associated Non-Coding RNAs.
MA583299 - JP 2018138019-A/155225: Polycomb-Associated Non-Coding RNAs.
MA583300 - JP 2018138019-A/155226: Polycomb-Associated Non-Coding RNAs.
MA583301 - JP 2018138019-A/155227: Polycomb-Associated Non-Coding RNAs.
MA441318 - JP 2018138019-A/13244: Polycomb-Associated Non-Coding RNAs.
MA449429 - JP 2018138019-A/21355: Polycomb-Associated Non-Coding RNAs.

-  Biochemical and Signaling Pathways
  BioCarta from NCI Cancer Genome Anatomy Project
h_edg1Pathway - Phospholipids as signalling intermediaries

Reactome (by CSHL, EBI, and GO)

Protein P06756 (Reactome details) participates in the following event(s):

R-HSA-210304 Interaction of integrin alphaVbeta3 with PECAM1
R-HSA-265423 Interaction of integrin alphaVbeta3 with Fibrillin
R-HSA-265425 Interaction of integrin alphaVbeta3 with von Willbrand Factor
R-HSA-265426 Interaction of integrin alphaVbeta3 with Tenascin
R-HSA-265427 Interaction of integrin alphaVbeta3 with IPSP (Bone sialoprotein 2)
R-NUL-2731085 Syndecan-1 binds integrin alphaVbeta3
R-HSA-2731123 Syndecan-1 binds Integrin alphaVbeta3
R-HSA-4086200 Dentin matrix protein 1 binds integrin alphaVbeta3
R-HSA-4088218 Tetrastatin binds integrin alphaVbeta3
R-HSA-5218818 Integrin alphaVbeta3 binds p-6Y-VEGFR2
R-HSA-4086132 Dentin phosphoprotein binds integrin alphaVbeta1
R-HSA-2731081 Syndecan-1 binds Integrin alphaVBeta5
R-HSA-6799350 Exocytosis of specific granule membrane proteins
R-HSA-5218836 PTK2beta binds alphaVbeta3
R-HSA-374686 L1 interaction with Integrins
R-HSA-2395320 Latent TGF-beta-1 binds integrins
R-HSA-2328037 Fibrillin-1 binds integrins
R-HSA-2396029 Latent TGF-beta-3 binds integrins
R-HSA-2426259 COMP binds Integrin alpha5beta1, Integrin alphaVbeta3, CD47
R-HSA-2426471 VTN binds integrins alphaVbeta1, alphaVbeta3, alpha3beta5, alphaIIBbeta3
R-HSA-2681667 TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1
R-HSA-2731074 Syndecan-1 binds Integrins alpha2beta1, (alpha6beta4)
R-HSA-2752125 SPP1 (osteopontin) binds integrins alphaVbeta1, alphaVbeta3, alphaVbeta5
R-HSA-4085083 Tumstatin binds integrin alphaVbeta 3, alpha3beta1
R-HSA-4085087 Canstatin binds integrins alphaVbeta3, alphaVbeta5
R-HSA-4088264 Endostatin binds integrin alphaVbeta3, alphaVbeta5, alpha3beta1, alpha5beta1
R-HSA-216050 Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix
R-HSA-216076 VTN (vitronectin) binds Integrin alphaVbeta3, alphaVbeta5, alphaVbeta8
R-HSA-2467436 AGRN binds Integrins alphaVbeta1 (Other beta1-containing integrins)
R-HSA-216051 Integrin alpha6beta1, alpha7beta1, alpha1beta1, alpha2beta1 bind laminin-111
R-NUL-3907289 Integrin alpha6beta1, alpha7beta1, alpha1beta1, alpha2beta1, alphaVbeta1 bind laminin-111
R-HSA-1236958 Interaction of particulate antigens with dendritic cell receptors
R-HSA-1236956 Engulfment of particulate antigen into phagocytic vesicle
R-HSA-5218830 SRC-1 phosphorylates PTK2-beta
R-HSA-5218851 p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407
R-HSA-210990 PECAM1 interactions
R-HSA-216083 Integrin cell surface interactions
R-HSA-3000170 Syndecan interactions
R-HSA-3000178 ECM proteoglycans
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-6798695 Neutrophil degranulation
R-HSA-445144 Signal transduction by L1
R-HSA-2129379 Molecules associated with elastic fibres
R-HSA-1566948 Elastic fibre formation
R-HSA-202733 Cell surface interactions at the vascular wall
R-HSA-1474244 Extracellular matrix organization
R-HSA-3000171 Non-integrin membrane-ECM interactions
R-HSA-194138 Signaling by VEGF
R-HSA-3000157 Laminin interactions
R-HSA-1236973 Cross-presentation of particulate exogenous antigens (phagosomes)
R-HSA-168249 Innate Immune System
R-HSA-373760 L1CAM interactions
R-HSA-109582 Hemostasis
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-1236975 Antigen processing-Cross presentation
R-HSA-168256 Immune System
R-HSA-422475 Axon guidance
R-HSA-162582 Signal Transduction
R-HSA-983169 Class I MHC mediated antigen processing & presentation
R-HSA-1266738 Developmental Biology
R-HSA-1280218 Adaptive Immune System

-  Other Names for This Gene
  Alternate Gene Symbols: A0AV67, B0LPF4, B7Z883, B7ZLX0, D3DPG8, E7EWZ6, ENST00000261023.1, ENST00000261023.2, ENST00000261023.3, ENST00000261023.4, ENST00000261023.5, ENST00000261023.6, ENST00000261023.7, ITAV_HUMAN, ITGAV , MSK8 , NM_002210, P06756, Q53SK4, Q59EB7, Q6LD15, uc317gmr.1, uc317gmr.2, VNRA , VTNR
UCSC ID: ENST00000261023.8_7
RefSeq Accession: NM_002210.5
Protein: P06756 (aka ITAV_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.