The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 47454 - A DNA-binding domain in eukaryotic transcription factors 57959 - Leucine zipper domain
ModBase Predicted Comparative 3D Structure on Q5U079
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0003677 DNA binding GO:0003700 transcription factor activity, sequence-specific DNA binding
Biological Process: GO:0001570 vasculogenesis GO:0001649 osteoblast differentiation GO:0001701 in utero embryonic development GO:0001829 trophectodermal cell differentiation GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0006366 transcription from RNA polymerase II promoter GO:0009987 cellular process GO:0030316 osteoclast differentiation GO:0033687 osteoblast proliferation GO:0045597 positive regulation of cell differentiation GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0046697 decidualization GO:0051726 regulation of cell cycle GO:0060136 embryonic process involved in female pregnancy GO:0060716 labyrinthine layer blood vessel development GO:0071277 cellular response to calcium ion
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
