Human Gene KHSRP (ENST00000600480.2_8) from GENCODE V47lift37
  Description: KH-type splicing regulatory protein, transcript variant 2 (from RefSeq NM_001366299.1)
Gencode Transcript: ENST00000600480.2_8
Gencode Gene: ENSG00000088247.19_16
Transcript (Including UTRs)
   Position: hg19 chr19:6,413,113-6,424,822 Size: 11,710 Total Exon Count: 19 Strand: -
Coding Region
   Position: hg19 chr19:6,415,035-6,424,712 Size: 9,678 Coding Exon Count: 19 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:6,413,113-6,424,822)mRNA (may differ from genome)Protein (747 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: KHSRP
Diseases sorted by gene-association score: ataxia, cerebellar, cayman type (3)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 72.95 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 1693.01 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -41.90110-0.381 Picture PostScript Text
3' UTR -626.001922-0.326 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  LF210896 - JP 2014500723-A/18399: Polycomb-Associated Non-Coding RNAs.
U94832 - Human KH type splicing regulatory protein KSRP mRNA, complete cds.
BC085004 - Homo sapiens KH-type splicing regulatory protein, mRNA (cDNA clone MGC:99676 IMAGE:6597976), complete cds.
GQ900928 - Homo sapiens clone HEL-T-40 epididymis secretory sperm binding protein mRNA, complete cds.
U69126 - Human FUSE binding protein 2 (FBP2) mRNA, partial cds.
AK300957 - Homo sapiens cDNA FLJ51330 complete cds, highly similar to Far upstream element-binding protein 2.
MA446473 - JP 2018138019-A/18399: Polycomb-Associated Non-Coding RNAs.
LF341776 - JP 2014500723-A/149279: Polycomb-Associated Non-Coding RNAs.
JD043789 - Sequence 24813 from Patent EP1572962.
LF341777 - JP 2014500723-A/149280: Polycomb-Associated Non-Coding RNAs.
JD389537 - Sequence 370561 from Patent EP1572962.
JD203264 - Sequence 184288 from Patent EP1572962.
LF341778 - JP 2014500723-A/149281: Polycomb-Associated Non-Coding RNAs.
JD359424 - Sequence 340448 from Patent EP1572962.
JD363570 - Sequence 344594 from Patent EP1572962.
JD502680 - Sequence 483704 from Patent EP1572962.
JD341089 - Sequence 322113 from Patent EP1572962.
LF341780 - JP 2014500723-A/149283: Polycomb-Associated Non-Coding RNAs.
JD259322 - Sequence 240346 from Patent EP1572962.
JD544323 - Sequence 525347 from Patent EP1572962.
JD551117 - Sequence 532141 from Patent EP1572962.
LF341785 - JP 2014500723-A/149288: Polycomb-Associated Non-Coding RNAs.
LF341788 - JP 2014500723-A/149291: Polycomb-Associated Non-Coding RNAs.
LF341789 - JP 2014500723-A/149292: Polycomb-Associated Non-Coding RNAs.
AB209662 - Homo sapiens mRNA for KH-type splicing regulatory protein (FUSE binding protein 2) variant protein.
HZ409199 - JP 2015528002-A/1796: CHIRAL CONTROL.
HZ460248 - WO 2015190542-A/254: Kit or device and method for detecting biliary tract cancer.
HZ461123 - WO 2015190584-A/620: Kit or device and method for detecting prostate cancer.
HZ461569 - WO 2015190586-A/382: Kit and method for detecting colon cancer.
HZ462166 - WO 2015190591-A/321: Kit and method for detecting breast cancer.
HZ463811 - WO 2015194610-A/247: Kit and method for detecting lung cancer.
HZ464494 - WO 2015194615-A/312: Kit or device and method for detecting hepatic cancer.
HZ465306 - WO 2015194627-A/359: Kit and method for detecting esophageal cancer.
LG052533 - KR 1020150036642-A/1799: CHIRAL CONTROL.
LY495875 - KR 1020170015509-A/254: DETECTION KIT OR DEVICE AND DETECTION METHOD FOR BILIARY TRACT CANCER.
LY496489 - KR 1020170018406-A/359: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497212 - KR 1020170016485-A/382: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY497712 - KR 1020170018409-A/247: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD.
LY498395 - KR 1020170018411-A/312: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LY499169 - KR 1020170018412-A/321: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER.
LY500996 - KR 1020170016490-A/620: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD.
LZ238710 - WO 2017171048-A/371: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas.
MS869040 - Sequence 254 from Patent EP3156500.
MS869915 - Sequence 620 from Patent EP3156483.
MS880484 - Sequence 321 from Patent EP3156498.
MS884399 - Sequence 382 from Patent EP3156499.
MS994497 - Sequence 359 from Patent EP3159406.
MS996778 - Sequence 247 from Patent EP3159416.
LF341793 - JP 2014500723-A/149296: Polycomb-Associated Non-Coding RNAs.
LF341794 - JP 2014500723-A/149297: Polycomb-Associated Non-Coding RNAs.
BD450071 - Screening method of agents for treating proliferative diseases.
LF341796 - JP 2014500723-A/149299: Polycomb-Associated Non-Coding RNAs.
MA577353 - JP 2018138019-A/149279: Polycomb-Associated Non-Coding RNAs.
MA577354 - JP 2018138019-A/149280: Polycomb-Associated Non-Coding RNAs.
MA577355 - JP 2018138019-A/149281: Polycomb-Associated Non-Coding RNAs.
MA577357 - JP 2018138019-A/149283: Polycomb-Associated Non-Coding RNAs.
MA577362 - JP 2018138019-A/149288: Polycomb-Associated Non-Coding RNAs.
MA577365 - JP 2018138019-A/149291: Polycomb-Associated Non-Coding RNAs.
MA577366 - JP 2018138019-A/149292: Polycomb-Associated Non-Coding RNAs.
MA577370 - JP 2018138019-A/149296: Polycomb-Associated Non-Coding RNAs.
MA577371 - JP 2018138019-A/149297: Polycomb-Associated Non-Coding RNAs.
MA577373 - JP 2018138019-A/149299: Polycomb-Associated Non-Coding RNAs.
MA806022 - WO 2018199275-A/282: Kit, device and method for detection of ovary tumor.
MA822739 - WO 2019004436-A/552: Kit, device, and method for detection of lung cancer.
LY616474 - KR 1020180129785-A/371: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR.
MB407003 - WO 2019159884-A/493: Kit, device, and method for detection of dementia.
MB472899 - WO 2019208671-A/298: Kit or device and method for detecting bladder cancer.
BC009473 - Homo sapiens, KH-type splicing regulatory protein (FUSE binding protein 2), clone IMAGE:4276204, mRNA.
JD520417 - Sequence 501441 from Patent EP1572962.
JD131786 - Sequence 112810 from Patent EP1572962.
JD406060 - Sequence 387084 from Patent EP1572962.
JD406057 - Sequence 387081 from Patent EP1572962.
JD458511 - Sequence 439535 from Patent EP1572962.
JD458512 - Sequence 439536 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000600480.1, hCG_23049 , KHSRP , M0R0C6, M0R0C6_HUMAN, NM_001366299, uc327evp.1, uc327evp.2
UCSC ID: ENST00000600480.2_8
RefSeq Accession: NM_001366299.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.