Human Gene KIF5B (ENST00000302418.5_7) from GENCODE V47lift37
  Description: kinesin family member 5B (from RefSeq NM_004521.3)
Gencode Transcript: ENST00000302418.5_7
Gencode Gene: ENSG00000170759.11_9
Transcript (Including UTRs)
   Position: hg19 chr10:32,297,943-32,345,353 Size: 47,411 Total Exon Count: 26 Strand: -
Coding Region
   Position: hg19 chr10:32,304,457-32,344,901 Size: 40,445 Coding Exon Count: 25 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:32,297,943-32,345,353)mRNA (may differ from genome)Protein (963 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: KIF5B
Diseases sorted by gene-association score: adenosquamous cell lung carcinoma (15), blackwater fever (9)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 91.95 RPKM in Brain - Spinal cord (cervical c-1)
Total median expression: 1746.88 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -226.10452-0.500 Picture PostScript Text
3' UTR -581.202522-0.230 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  LF213669 - JP 2014500723-A/21172: Polycomb-Associated Non-Coding RNAs.
LF210959 - JP 2014500723-A/18462: Polycomb-Associated Non-Coding RNAs.
LF348478 - JP 2014500723-A/155981: Polycomb-Associated Non-Coding RNAs.
LF342531 - JP 2014500723-A/150034: Polycomb-Associated Non-Coding RNAs.
LF348477 - JP 2014500723-A/155980: Polycomb-Associated Non-Coding RNAs.
LF342532 - JP 2014500723-A/150035: Polycomb-Associated Non-Coding RNAs.
LF342533 - JP 2014500723-A/150036: Polycomb-Associated Non-Coding RNAs.
LF342534 - JP 2014500723-A/150037: Polycomb-Associated Non-Coding RNAs.
JD026589 - Sequence 7613 from Patent EP1572962.
JD029336 - Sequence 10360 from Patent EP1572962.
LF342535 - JP 2014500723-A/150038: Polycomb-Associated Non-Coding RNAs.
LF342536 - JP 2014500723-A/150039: Polycomb-Associated Non-Coding RNAs.
AK299542 - Homo sapiens cDNA FLJ51288 complete cds, highly similar to Kinesin heavy chain.
FJ224324 - Homo sapiens epididymis secretory protein Li 61 (HEL-S-61) mRNA, complete cds.
X65873 - H.sapiens mRNA for kinesin (heavy chain).
JD300881 - Sequence 281905 from Patent EP1572962.
JD295230 - Sequence 276254 from Patent EP1572962.
JD262318 - Sequence 243342 from Patent EP1572962.
BC126279 - Homo sapiens kinesin family member 5B, mRNA (cDNA clone MGC:161557 IMAGE:8991995), complete cds.
BC126281 - Homo sapiens kinesin family member 5B, mRNA (cDNA clone MGC:161559 IMAGE:8991997), complete cds.
JD477558 - Sequence 458582 from Patent EP1572962.
AB462413 - Homo sapiens KIF5B-ALK mRNA for fusion protein KIF5B-ALK, complete cds.
AB795257 - Homo sapiens KIF5B-RET(NM_020630)_K24;R11 mRNA for KIF5B-RET(NM_020630)_K24;R11 fusion protein, complete cds.
LF342537 - JP 2014500723-A/150040: Polycomb-Associated Non-Coding RNAs.
AK289413 - Homo sapiens cDNA FLJ76989 partial cds, highly similar to Homo sapiens kinesin family member 5B (KIF5B), mRNA.
AB795255 - Homo sapiens KIF5B-RET(NM_020630)_K23;R12 mRNA for KIF5B-RET(NM_020630)_K23;R12 fusion protein, complete cds.
AB795256 - Homo sapiens KIF5B-RET(NM_020975)_K23;R12 mRNA for KIF5B-RET(NM_020975)_K23;R12 fusion protein, complete cds.
AB795253 - Homo sapiens KIF5B-RET(NM_020630)_K22;R12 mRNA for KIF5B-RET(NM_020630)_K22;R12 fusion protein, complete cds.
AB795254 - Homo sapiens KIF5B-RET(NM_020975)_K22;R12 mRNA for KIF5B-RET(NM_020975)_K22;R12 fusion protein, complete cds.
LF342538 - JP 2014500723-A/150041: Polycomb-Associated Non-Coding RNAs.
LF342539 - JP 2014500723-A/150042: Polycomb-Associated Non-Coding RNAs.
LF342540 - JP 2014500723-A/150043: Polycomb-Associated Non-Coding RNAs.
LF210960 - JP 2014500723-A/18463: Polycomb-Associated Non-Coding RNAs.
AB795238 - Homo sapiens KIF5B-ALK_K17;A20 mRNA for KIF5B-ALK_K17;A20 fusion protein, complete cds.
LF342542 - JP 2014500723-A/150045: Polycomb-Associated Non-Coding RNAs.
AB795251 - Homo sapiens KIF5B-RET(NM_020630)_K16;R12 mRNA for KIF5B-RET(NM_020630)_K16;R12 fusion protein, complete cds.
AB795252 - Homo sapiens KIF5B-RET(NM_020975)_K16;R12 mRNA for KIF5B-RET(NM_020975)_K16;R12 fusion protein, complete cds.
LF342544 - JP 2014500723-A/150047: Polycomb-Associated Non-Coding RNAs.
AK307502 - Homo sapiens cDNA, FLJ97450.
AB795249 - Homo sapiens KIF5B-RET(NM_020630)_K15;R12 mRNA for KIF5B-RET(NM_020630)_K15;R12 fusion protein, complete cds.
AB795250 - Homo sapiens KIF5B-RET(NM_020975)_K15;R12 mRNA for KIF5B-RET(NM_020975)_K15;R12 fusion protein, complete cds.
LF342545 - JP 2014500723-A/150048: Polycomb-Associated Non-Coding RNAs.
LF342548 - JP 2014500723-A/150051: Polycomb-Associated Non-Coding RNAs.
LF342549 - JP 2014500723-A/150052: Polycomb-Associated Non-Coding RNAs.
LF342550 - JP 2014500723-A/150053: Polycomb-Associated Non-Coding RNAs.
LF342551 - JP 2014500723-A/150054: Polycomb-Associated Non-Coding RNAs.
LF342552 - JP 2014500723-A/150055: Polycomb-Associated Non-Coding RNAs.
BC080604 - Homo sapiens kinesin family member 5B, mRNA (cDNA clone IMAGE:5020096), partial cds.
BC010885 - Homo sapiens kinesin family member 5B, mRNA (cDNA clone IMAGE:3538563).
BC111042 - Homo sapiens kinesin family member 5B, mRNA (cDNA clone IMAGE:5529261), partial cds.
BC065267 - Homo sapiens kinesin family member 5B, mRNA (cDNA clone IMAGE:6155720), partial cds.
LF342553 - JP 2014500723-A/150056: Polycomb-Associated Non-Coding RNAs.
LF342554 - JP 2014500723-A/150057: Polycomb-Associated Non-Coding RNAs.
LF342555 - JP 2014500723-A/150058: Polycomb-Associated Non-Coding RNAs.
JD347044 - Sequence 328068 from Patent EP1572962.
LF342564 - JP 2014500723-A/150067: Polycomb-Associated Non-Coding RNAs.
JD399255 - Sequence 380279 from Patent EP1572962.
JD461146 - Sequence 442170 from Patent EP1572962.
JD407735 - Sequence 388759 from Patent EP1572962.
JD478831 - Sequence 459855 from Patent EP1572962.
JD200340 - Sequence 181364 from Patent EP1572962.
JD271298 - Sequence 252322 from Patent EP1572962.
JD464373 - Sequence 445397 from Patent EP1572962.
MA584055 - JP 2018138019-A/155981: Polycomb-Associated Non-Coding RNAs.
MA578108 - JP 2018138019-A/150034: Polycomb-Associated Non-Coding RNAs.
MA584054 - JP 2018138019-A/155980: Polycomb-Associated Non-Coding RNAs.
MA578109 - JP 2018138019-A/150035: Polycomb-Associated Non-Coding RNAs.
MA578110 - JP 2018138019-A/150036: Polycomb-Associated Non-Coding RNAs.
MA578111 - JP 2018138019-A/150037: Polycomb-Associated Non-Coding RNAs.
MA578112 - JP 2018138019-A/150038: Polycomb-Associated Non-Coding RNAs.
MA578113 - JP 2018138019-A/150039: Polycomb-Associated Non-Coding RNAs.
MA578114 - JP 2018138019-A/150040: Polycomb-Associated Non-Coding RNAs.
MA578115 - JP 2018138019-A/150041: Polycomb-Associated Non-Coding RNAs.
MA578116 - JP 2018138019-A/150042: Polycomb-Associated Non-Coding RNAs.
MA578117 - JP 2018138019-A/150043: Polycomb-Associated Non-Coding RNAs.
MA578119 - JP 2018138019-A/150045: Polycomb-Associated Non-Coding RNAs.
MA578121 - JP 2018138019-A/150047: Polycomb-Associated Non-Coding RNAs.
MA578122 - JP 2018138019-A/150048: Polycomb-Associated Non-Coding RNAs.
MA578125 - JP 2018138019-A/150051: Polycomb-Associated Non-Coding RNAs.
MA578126 - JP 2018138019-A/150052: Polycomb-Associated Non-Coding RNAs.
MA578127 - JP 2018138019-A/150053: Polycomb-Associated Non-Coding RNAs.
MA578128 - JP 2018138019-A/150054: Polycomb-Associated Non-Coding RNAs.
MA578129 - JP 2018138019-A/150055: Polycomb-Associated Non-Coding RNAs.
MA578130 - JP 2018138019-A/150056: Polycomb-Associated Non-Coding RNAs.
MA578131 - JP 2018138019-A/150057: Polycomb-Associated Non-Coding RNAs.
MA578132 - JP 2018138019-A/150058: Polycomb-Associated Non-Coding RNAs.
MA578141 - JP 2018138019-A/150067: Polycomb-Associated Non-Coding RNAs.
MA449246 - JP 2018138019-A/21172: Polycomb-Associated Non-Coding RNAs.
MA446536 - JP 2018138019-A/18462: Polycomb-Associated Non-Coding RNAs.
MA446537 - JP 2018138019-A/18463: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000302418.1, ENST00000302418.2, ENST00000302418.3, ENST00000302418.4, HEL-S-61 , NM_004521, uc317naq.1, uc317naq.2, V9HW29, V9HW29_HUMAN
UCSC ID: ENST00000302418.5_7
RefSeq Accession: NM_004521.3

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.