ID:K1C39_HUMAN DESCRIPTION: RecName: Full=Keratin, type I cytoskeletal 39; AltName: Full=Cytokeratin-39; Short=CK-39; AltName: Full=Keratin-39; Short=K39; AltName: Full=Type I hair keratin Ka35; FUNCTION: May play a role in late hair differentiation. SUBUNIT: Heterotetramer of two type I and two type II keratins. TISSUE SPECIFICITY: Expressed in skin and scalp. In the hair follicle, it is present in the upper hair cuticle and the upper cortex. Also present in the in the upper portion of beard hairs (at protein level). DEVELOPMENTAL STAGE: During differentiation of the hair, it is one of the last keratins expressed. MISCELLANEOUS: There are two types of cytoskeletal and microfibrillar keratin, I (acidic) and II (neutral to basic) (40- 55 and 56-70 kDa, respectively). SIMILARITY: Belongs to the intermediate filament family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6A163
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
