ID:LSP1_HUMAN DESCRIPTION: RecName: Full=Lymphocyte-specific protein 1; AltName: Full=47 kDa actin-binding protein; AltName: Full=52 kDa phosphoprotein; Short=pp52; AltName: Full=Lymphocyte-specific antigen WP34; FUNCTION: May play a role in mediating neutrophil activation and chemotaxis (By similarity). SUBUNIT: Binds actin. SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein; Cytoplasmic side. TISSUE SPECIFICITY: Activated T-lymphocytes. PTM: Phosphorylated by casein kinase II, protein kinase C and MAPKAPK2. Phosphorylation by PKC induces translocation from membrane to cytoplasm. Phosphorylation by MAPKAPK2 may regulate neutrophil chemotaxis (By similarity).
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P33241
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
LF207981 - JP 2014500723-A/15484: Polycomb-Associated Non-Coding RNAs. AK222733 - Homo sapiens mRNA for lymphocyte-specific protein 1 variant, clone: DMC01679. JD236682 - Sequence 217706 from Patent EP1572962. M33552 - Human lymphocyte-specific protein 1 (LSP1) mRNA, complete cds. BC001785 - Homo sapiens lymphocyte-specific protein 1, mRNA (cDNA clone MGC:2290 IMAGE:3542307), complete cds. JD100973 - Sequence 81997 from Patent EP1572962. X55188 - H.sapiens mRNA WP34 for phosphorylated lymphocyte differentiation and activation antigen. AK290279 - Homo sapiens cDNA FLJ76079 complete cds, highly similar to Homo sapiens lymphocyte-specific protein 1 (LSP1), mRNA. S67783 - lymphocyte-specific protein 1=47 kda actin binding protein [human, HL60, mRNA, 1039 nt]. CU674886 - Synthetic construct Homo sapiens gateway clone IMAGE:100017046 5' read LSP1 mRNA. CR541754 - Homo sapiens full open reading frame cDNA clone RZPDo834H1029D for gene LSP1, lymphocyte-specific protein 1; complete cds, without stopcodon. KJ897144 - Synthetic construct Homo sapiens clone ccsbBroadEn_06538 LSP1 gene, encodes complete protein. CR541728 - Homo sapiens full open reading frame cDNA clone RZPDo834D1029D for gene LSP1, lymphocyte-specific protein 1; complete cds, incl. stopcodon. AK092071 - Homo sapiens cDNA FLJ34752 fis, clone NESOP2000452, highly similar to Lymphocyte-specific protein 1. AX747343 - Sequence 868 from Patent EP1308459. AK056576 - Homo sapiens cDNA FLJ32014 fis, clone NTONG1000047, highly similar to Lymphocyte-specific protein 1. AK292033 - Homo sapiens cDNA FLJ77847 complete cds. HZ459683 - WO 2015182781-A/386: Kit or device and method for detecting pancreatic cancer. HZ460242 - WO 2015190542-A/248: Kit or device and method for detecting biliary tract cancer. HZ460748 - WO 2015190584-A/245: Kit or device and method for detecting prostate cancer. HZ461456 - WO 2015190586-A/269: Kit and method for detecting colon cancer. HZ462263 - WO 2015190591-A/418: Kit and method for detecting breast cancer. HZ463184 - WO 2015194535-A/278: Kit and method for detecting stomach cancer. HZ463840 - WO 2015194610-A/276: Kit and method for detecting lung cancer. HZ464556 - WO 2015194615-A/374: Kit or device and method for detecting hepatic cancer. HZ465227 - WO 2015194627-A/280: Kit and method for detecting esophageal cancer. LY481123 - KR 1020170010856-A/386: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD. LY495869 - KR 1020170015509-A/248: DETECTION KIT OR DEVICE AND DETECTION METHOD FOR BILIARY TRACT CANCER. LY496410 - KR 1020170018406-A/280: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY497099 - KR 1020170016485-A/269: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY497741 - KR 1020170018409-A/276: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD. LY498457 - KR 1020170018411-A/374: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY499266 - KR 1020170018412-A/418: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER. LY499997 - KR 1020170019425-A/278: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY500621 - KR 1020170016490-A/245: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LZ238702 - WO 2017171048-A/363: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas. MS869034 - Sequence 248 from Patent EP3156500. MS869540 - Sequence 245 from Patent EP3156483. MS880581 - Sequence 418 from Patent EP3156498. MS884286 - Sequence 269 from Patent EP3156499. MS885116 - Sequence 278 from Patent EP3156503. MS994418 - Sequence 280 from Patent EP3159406. MS996807 - Sequence 276 from Patent EP3159416. HZ459648 - WO 2015182781-A/351: Kit or device and method for detecting pancreatic cancer. HZ460091 - WO 2015190542-A/97: Kit or device and method for detecting biliary tract cancer. HZ460562 - WO 2015190584-A/59: Kit or device and method for detecting prostate cancer. HZ461262 - WO 2015190586-A/75: Kit and method for detecting colon cancer. HZ461985 - WO 2015190591-A/140: Kit and method for detecting breast cancer. HZ462985 - WO 2015194535-A/79: Kit and method for detecting stomach cancer. HZ463665 - WO 2015194610-A/101: Kit and method for detecting lung cancer. HZ464338 - WO 2015194615-A/156: Kit or device and method for detecting hepatic cancer. HZ465012 - WO 2015194627-A/65: Kit and method for detecting esophageal cancer. LP951755 - Sequence 261 from Patent WO2017157650. LQ724809 - Sequence 442 from Patent WO2018096084. LY481088 - KR 1020170010856-A/351: PANCREATIC CANCER DETECTION KIT, DEVICE, AND DETECTION METHOD. LY495718 - KR 1020170015509-A/97: DETECTION KIT OR DEVICE AND DETECTION METHOD FOR BILIARY TRACT CANCER. LY496195 - KR 1020170018406-A/65: ESOPHAGEAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY496905 - KR 1020170016485-A/75: COLORECTAL CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY497566 - KR 1020170018409-A/101: KIT OR DEVICE FOR DETECTING LUNG CANCER, AND LUNG CANCER DETECTION METHOD. LY498239 - KR 1020170018411-A/156: LIVER CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY498988 - KR 1020170018412-A/140: BREAST CANCER DETECTION KIT OR DEVICE, AND METHOD FOR DETECTING BREAST CANCER. LY499798 - KR 1020170019425-A/79: STOMACH CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LY500435 - KR 1020170016490-A/59: PROSTATE CANCER DETECTION KIT OR DEVICE, AND DETECTION METHOD. LZ238446 - WO 2017171048-A/107: Kit, device and method for detecting early pancreatic cancer or precancerous lesion of pancreas. MS868883 - Sequence 97 from Patent EP3156500. MS869354 - Sequence 59 from Patent EP3156483. MS880303 - Sequence 140 from Patent EP3156498. MS884092 - Sequence 75 from Patent EP3156499. MS884917 - Sequence 79 from Patent EP3156503. MS994203 - Sequence 65 from Patent EP3159406. MS996632 - Sequence 101 from Patent EP3159416. AK093859 - Homo sapiens cDNA FLJ36540 fis, clone TRACH2005710, highly similar to LYMPHOCYTE-SPECIFIC PROTEIN LSP1. LF370690 - JP 2014500723-A/178193: Polycomb-Associated Non-Coding RNAs. LF370691 - JP 2014500723-A/178194: Polycomb-Associated Non-Coding RNAs. MS906505 - Sequence 59 from Patent WO2017059902. MS909311 - Sequence 59 from Patent WO2017060314. MS906504 - Sequence 58 from Patent WO2017059902. MS909310 - Sequence 58 from Patent WO2017060314. MS906514 - Sequence 68 from Patent WO2017059902. MS909320 - Sequence 68 from Patent WO2017060314. AK129684 - Homo sapiens cDNA FLJ26173 fis, clone ADG03859. MS906503 - Sequence 57 from Patent WO2017059902. MS909309 - Sequence 57 from Patent WO2017060314. MS906501 - Sequence 55 from Patent WO2017059902. MS909307 - Sequence 55 from Patent WO2017060314. MS906499 - Sequence 53 from Patent WO2017059902. MS909305 - Sequence 53 from Patent WO2017060314. JD493879 - Sequence 474903 from Patent EP1572962. MS906515 - Sequence 69 from Patent WO2017059902. MS909321 - Sequence 69 from Patent WO2017060314. MS906510 - Sequence 64 from Patent WO2017059902. MS909316 - Sequence 64 from Patent WO2017060314. MS906509 - Sequence 63 from Patent WO2017059902. MS909315 - Sequence 63 from Patent WO2017060314. MS906502 - Sequence 56 from Patent WO2017059902. MS909308 - Sequence 56 from Patent WO2017060314. MS906506 - Sequence 60 from Patent WO2017059902. MS909312 - Sequence 60 from Patent WO2017060314. MS906498 - Sequence 52 from Patent WO2017059902. MS909304 - Sequence 52 from Patent WO2017060314. MS906516 - Sequence 70 from Patent WO2017059902. MS909322 - Sequence 70 from Patent WO2017060314. MS906500 - Sequence 54 from Patent WO2017059902. MS909306 - Sequence 54 from Patent WO2017060314. MS906513 - Sequence 67 from Patent WO2017059902. MS909319 - Sequence 67 from Patent WO2017060314. MS906511 - Sequence 65 from Patent WO2017059902. MS909317 - Sequence 65 from Patent WO2017060314. MS906518 - Sequence 72 from Patent WO2017059902. MS909324 - Sequence 72 from Patent WO2017060314. MS906512 - Sequence 66 from Patent WO2017059902. MS909318 - Sequence 66 from Patent WO2017060314. MS906497 - Sequence 51 from Patent WO2017059902. MS909303 - Sequence 51 from Patent WO2017060314. MS906517 - Sequence 71 from Patent WO2017059902. MS909323 - Sequence 71 from Patent WO2017060314. MS906508 - Sequence 62 from Patent WO2017059902. MS909314 - Sequence 62 from Patent WO2017060314. MS906507 - Sequence 61 from Patent WO2017059902. MS909313 - Sequence 61 from Patent WO2017060314. JD042810 - Sequence 23834 from Patent EP1572962. JD195408 - Sequence 176432 from Patent EP1572962. JD074013 - Sequence 55037 from Patent EP1572962. JD473485 - Sequence 454509 from Patent EP1572962. JD394434 - Sequence 375458 from Patent EP1572962. MA606267 - JP 2018138019-A/178193: Polycomb-Associated Non-Coding RNAs. MA606268 - JP 2018138019-A/178194: Polycomb-Associated Non-Coding RNAs. MA443558 - JP 2018138019-A/15484: Polycomb-Associated Non-Coding RNAs. MA806182 - WO 2018199275-A/442: Kit, device and method for detection of ovary tumor. MA805905 - WO 2018199275-A/165: Kit, device and method for detection of ovary tumor. MA822820 - WO 2019004436-A/633: Kit, device, and method for detection of lung cancer. MA822485 - WO 2019004436-A/298: Kit, device, and method for detection of lung cancer. LY616466 - KR 1020180129785-A/363: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR. LY616210 - KR 1020180129785-A/107: KIT OR DEVICE FOR DETECTING EARLY STAGE PANCREATIC CANCER OR PANCREATIC CANCER PRECURSOR LESIONS AND DETECTION METHOD THEREFOR. MP573172 - Sequence 59 from Patent EP3636764. MP573171 - Sequence 58 from Patent EP3636764. MP573181 - Sequence 68 from Patent EP3636764. MP573170 - Sequence 57 from Patent EP3636764. MP573168 - Sequence 55 from Patent EP3636764. MP573166 - Sequence 53 from Patent EP3636764. MP573182 - Sequence 69 from Patent EP3636764. MP573177 - Sequence 64 from Patent EP3636764. MP573176 - Sequence 63 from Patent EP3636764. MP573169 - Sequence 56 from Patent EP3636764. MP573173 - Sequence 60 from Patent EP3636764. MP573165 - Sequence 52 from Patent EP3636764. MP573183 - Sequence 70 from Patent EP3636764. MP573167 - Sequence 54 from Patent EP3636764. MP573180 - Sequence 67 from Patent EP3636764. MP573178 - Sequence 65 from Patent EP3636764. MP573185 - Sequence 72 from Patent EP3636764. MP573179 - Sequence 66 from Patent EP3636764. MP573164 - Sequence 51 from Patent EP3636764. MP573184 - Sequence 71 from Patent EP3636764. MP573175 - Sequence 62 from Patent EP3636764. MP573174 - Sequence 61 from Patent EP3636764.
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
