Human Gene MAP4 (ENST00000683076.1_6) from GENCODE V47lift37

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Description: microtubule associated protein 4, transcript variant 140 (from RefSeq NM_001385689.1)
Gencode Transcript: ENST00000683076.1_6
Gencode Gene: ENSG00000047849.22_21
Transcript (Including UTRs)
Position: hg19 chr3:47,892,185-48,057,906 Size: 165,722 Total Exon Count: 21 Strand: -
Coding Region
Position: hg19 chr3:47,894,424-48,040,350 Size: 145,927 Coding Exon Count: 20

Page Index	Sequence and Links	Primers	MalaCards	CTD	Gene Alleles
Microarray Expression	RNA Structure	Other Species	mRNA Descriptions	Other Names	Model Information
Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr3:47,892,185-48,057,906)			mRNA (may differ from genome)		Protein (2296 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	Malacards	MGI	OMIM	PubMed	UniProtKB
Wikipedia	BioGrid CRISPR DB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

MalaCards Disease Associations


	MalaCards Gene Search: MAP4 Diseases sorted by gene-association score: ovarian clear cell adenocarcinoma (10), deafness, autosomal recessive 6 (7), dystonia-11, myoclonic (6)

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene D000082 Acetaminophen D001564 Benzo(a)pyrene D016572 Cyclosporine D004317 Doxorubicin D013749 Tetrachlorodibenzodioxin D000452 Aldrin D001554 Benzene D002945 Cisplatin D003300 Copper D003907 Dexamethasone more ... click here to view the complete list

Common Gene Haplotype Alleles


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Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-26.50	102	-0.260	Picture	PostScript	Text
3' UTR	-895.90	2239	-0.400	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Descriptions from all associated GenBank mRNAs


	LF384596 - JP 2014500723-A/192099: Polycomb-Associated Non-Coding RNAs. AB209377 - Homo sapiens mRNA for microtubule-associated protein 4 isoform 1 variant protein. BC008715 - Homo sapiens microtubule-associated protein 4, mRNA (cDNA clone MGC:8617 IMAGE:2961360), complete cds. BC012794 - Homo sapiens microtubule-associated protein 4, mRNA (cDNA clone MGC:16562 IMAGE:4098499), complete cds. BC015149 - Homo sapiens microtubule-associated protein 4, mRNA (cDNA clone MGC:3692 IMAGE:2961360), complete cds. M64571 - Human microtubule-associated protein 4 mRNA, complete cds. U19727 - Human microtubule-associated protein 4 (MAP4) mRNA, complete cds. AK297242 - Homo sapiens cDNA FLJ58263 complete cds, highly similar to Microtubule-associated protein 4. KJ901564 - Synthetic construct Homo sapiens clone ccsbBroadEn_10958 MAP4 gene, encodes complete protein. AK307606 - Homo sapiens cDNA, FLJ97554. BC067228 - Homo sapiens microtubule-associated protein 4, mRNA (cDNA clone IMAGE:4723117), partial cds. BC019229 - Homo sapiens microtubule-associated protein 4, mRNA (cDNA clone IMAGE:4096931), partial cds. AK054577 - Homo sapiens cDNA FLJ30015 fis, clone 3NB692000374, highly similar to MICROTUBULE-ASSOCIATED PROTEIN 4. CU679053 - Synthetic construct Homo sapiens gateway clone IMAGE:100017872 5' read MAP4 mRNA. BC051843 - Homo sapiens microtubule-associated protein 4, mRNA (cDNA clone IMAGE:5501722), complete cds. MA620173 - JP 2018138019-A/192099: Polycomb-Associated Non-Coding RNAs. AF454938 - Homo sapiens hypothetical protein mRNA, complete cds. AL831878 - Homo sapiens mRNA; cDNA DKFZp547H1810 (from clone DKFZp547H1810). CR749544 - Homo sapiens mRNA; cDNA DKFZp779A1753 (from clone DKFZp779A1753). BC048200 - Homo sapiens microtubule-associated protein 4, mRNA (cDNA clone IMAGE:3688177), partial cds. JD021394 - Sequence 2418 from Patent EP1572962. JD029128 - Sequence 10152 from Patent EP1572962. AF052156 - Homo sapiens clone 24562 mRNA sequence. JD232282 - Sequence 213306 from Patent EP1572962. JD459545 - Sequence 440569 from Patent EP1572962. JD200476 - Sequence 181500 from Patent EP1572962. JD284667 - Sequence 265691 from Patent EP1572962. JD037413 - Sequence 18437 from Patent EP1572962. JD420052 - Sequence 401076 from Patent EP1572962. JD493136 - Sequence 474160 from Patent EP1572962. JD218989 - Sequence 200013 from Patent EP1572962. JD367858 - Sequence 348882 from Patent EP1572962. JD385775 - Sequence 366799 from Patent EP1572962. AK299854 - Homo sapiens cDNA FLJ58279 complete cds, highly similar to Microtubule-associated protein 4. JD546077 - Sequence 527101 from Patent EP1572962. JD457783 - Sequence 438807 from Patent EP1572962. JD402071 - Sequence 383095 from Patent EP1572962. JD322033 - Sequence 303057 from Patent EP1572962. JD097631 - Sequence 78655 from Patent EP1572962. JD157224 - Sequence 138248 from Patent EP1572962. JD395916 - Sequence 376940 from Patent EP1572962. JD183762 - Sequence 164786 from Patent EP1572962. AK125245 - Homo sapiens cDNA FLJ43255 fis, clone HEART2010495, moderately similar to MICROTUBULE-ASSOCIATED PROTEIN 4. AK054696 - Homo sapiens cDNA FLJ30134 fis, clone BRACE1000187, weakly similar to MICROTUBULE-ASSOCIATED PROTEIN 4. BX649077 - Homo sapiens mRNA; cDNA DKFZp779C2156 (from clone DKFZp779C2156). EU831606 - Synthetic construct Homo sapiens clone HAIB:100066635; DKFZo007C0319 microtubule-associated protein 4 protein (MAP4) gene, encodes complete protein. EU831693 - Synthetic construct Homo sapiens clone HAIB:100066722; DKFZo003C0320 microtubule-associated protein 4 protein (MAP4) gene, encodes complete protein. JD454170 - Sequence 435194 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: A0A804HKE7, A0A804HKE7_HUMAN, MAP4 , NM_001385689, uc330kwc.1, uc330kwc.2 UCSC ID: ENST00000683076.1_6 RefSeq Accession: NM_001385682.1

Gene Model Information


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Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.