Human Gene MAP7D2 (ENST00000379643.10_11) from GENCODE V47lift37
  Description: MAP7 domain containing 2, transcript variant 1 (from RefSeq NM_001168465.2)
Gencode Transcript: ENST00000379643.10_11
Gencode Gene: ENSG00000184368.16_13
Transcript (Including UTRs)
   Position: hg19 chrX:20,024,831-20,135,025 Size: 110,195 Total Exon Count: 17 Strand: -
Coding Region
   Position: hg19 chrX:20,028,921-20,134,997 Size: 106,077 Coding Exon Count: 16 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:20,024,831-20,135,025)mRNA (may differ from genome)Protein (773 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIPubMedUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: MA7D2_HUMAN
DESCRIPTION: RecName: Full=MAP7 domain-containing protein 2;
SIMILARITY: Belongs to the MAP7 family.
SEQUENCE CAUTION: Sequence=BAC05407.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 21.50 RPKM in Brain - Frontal Cortex (BA9)
Total median expression: 179.73 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -12.3028-0.439 Picture PostScript Text
3' UTR -428.901712-0.251 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR008604 - E-MAP-115

Pfam Domains:
PF05672 - MAP7 (E-MAP-115) family

ModBase Predicted Comparative 3D Structure on Q96T17
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
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-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005198 structural molecule activity

Biological Process:
GO:0000226 microtubule cytoskeleton organization

Cellular Component:
GO:0015630 microtubule cytoskeleton


-  Descriptions from all associated GenBank mRNAs
  BC089400 - Homo sapiens MAP7 domain containing 2, mRNA (cDNA clone MGC:104944 IMAGE:3063898), complete cds.
AK127056 - Homo sapiens cDNA FLJ45113 fis, clone BRAWH3034743, weakly similar to Mus musculus microtubule-associated protein 7 (Mtap7), mRNA.
BC037165 - Homo sapiens MAP7 domain containing 2, mRNA (cDNA clone IMAGE:5087118), partial cds.
BC052256 - Homo sapiens MAP7 domain containing 2, mRNA (cDNA clone IMAGE:6299940), with apparent retained intron.
AK098768 - Homo sapiens cDNA FLJ25902 fis, clone CBR04408.
AK027409 - Homo sapiens cDNA FLJ14503 fis, clone NT2RM1000252, weakly similar to H.sapiens E-MAP-115 mRNA.
BC136379 - Homo sapiens MAP7 domain containing 2, mRNA (cDNA clone MGC:167989 IMAGE:9020366), complete cds.
AK316117 - Homo sapiens cDNA, FLJ79016 complete cds, weakly similar to Mus musculus microtubule-associated protein 7 (Mtap7), mRNA.
AK296319 - Homo sapiens cDNA FLJ57335 complete cds, weakly similar to Homo sapiens microtubule-associated protein 7 (MAP7), mRNA.
KP979782 - Homo sapiens MAP7 domain containing 2 brain transcript variant 1 (MAP7D2) mRNA, complete cds.
KP979783 - Homo sapiens MAP7 domain containing 2 brain transcript variant 2 (MAP7D2) mRNA, complete cds.
KP979784 - Homo sapiens MAP7 domain containing 2 brain transcript variant 3 (MAP7D2) mRNA, complete cds.
KP979785 - Homo sapiens MAP7 domain containing 2 brain transcript variant 4 (MAP7D2) mRNA, complete cds.
KP979786 - Homo sapiens MAP7 domain containing 2 transcript variant 5 (MAP7D2) mRNA, complete cds.
AK303019 - Homo sapiens cDNA FLJ57681 complete cds, weakly similar to Mus musculus microtubule-associated protein 7 (Mtap7), mRNA.
AK294788 - Homo sapiens cDNA FLJ58136 complete cds, weakly similar to Homo sapiens microtubule-associated protein 7 (MAP7), mRNA.
KP849473 - Homo sapiens MAP7 domain-containing protein 2 brain specific variant 1 mRNA, complete cds.
KP849474 - Homo sapiens MAP7 domain-containing protein 2 brain specific variant 2 mRNA, complete cds.
KJ900523 - Synthetic construct Homo sapiens clone ccsbBroadEn_09917 MAP7D2 gene, encodes complete protein.
JD567125 - Sequence 548149 from Patent EP1572962.
JD455873 - Sequence 436897 from Patent EP1572962.
JD507072 - Sequence 488096 from Patent EP1572962.
JD360366 - Sequence 341390 from Patent EP1572962.
JD263027 - Sequence 244051 from Patent EP1572962.
JD482101 - Sequence 463125 from Patent EP1572962.
JD147317 - Sequence 128341 from Patent EP1572962.
JD288501 - Sequence 269525 from Patent EP1572962.
JD281317 - Sequence 262341 from Patent EP1572962.
JD352249 - Sequence 333273 from Patent EP1572962.
JD208325 - Sequence 189349 from Patent EP1572962.
LF382986 - JP 2014500723-A/190489: Polycomb-Associated Non-Coding RNAs.
JD509431 - Sequence 490455 from Patent EP1572962.
JD243483 - Sequence 224507 from Patent EP1572962.
LF382985 - JP 2014500723-A/190488: Polycomb-Associated Non-Coding RNAs.
LF382983 - JP 2014500723-A/190486: Polycomb-Associated Non-Coding RNAs.
LF382981 - JP 2014500723-A/190484: Polycomb-Associated Non-Coding RNAs.
LF382979 - JP 2014500723-A/190482: Polycomb-Associated Non-Coding RNAs.
LF382978 - JP 2014500723-A/190481: Polycomb-Associated Non-Coding RNAs.
LF382977 - JP 2014500723-A/190480: Polycomb-Associated Non-Coding RNAs.
LF382972 - JP 2014500723-A/190475: Polycomb-Associated Non-Coding RNAs.
LF382971 - JP 2014500723-A/190474: Polycomb-Associated Non-Coding RNAs.
MA618563 - JP 2018138019-A/190489: Polycomb-Associated Non-Coding RNAs.
MA618562 - JP 2018138019-A/190488: Polycomb-Associated Non-Coding RNAs.
MA618560 - JP 2018138019-A/190486: Polycomb-Associated Non-Coding RNAs.
MA618558 - JP 2018138019-A/190484: Polycomb-Associated Non-Coding RNAs.
MA618556 - JP 2018138019-A/190482: Polycomb-Associated Non-Coding RNAs.
MA618555 - JP 2018138019-A/190481: Polycomb-Associated Non-Coding RNAs.
MA618554 - JP 2018138019-A/190480: Polycomb-Associated Non-Coding RNAs.
MA618549 - JP 2018138019-A/190475: Polycomb-Associated Non-Coding RNAs.
MA618548 - JP 2018138019-A/190474: Polycomb-Associated Non-Coding RNAs.
JQ319659 - Homo sapiens MAP7 domain containing 2 protein varaint 1 (MAP7D2) mRNA, partial cds.
JQ319660 - Homo sapiens MAP7 domain containing 2 protein varaint 2 (MAP7D2) mRNA, partial cds.
LF382964 - JP 2014500723-A/190467: Polycomb-Associated Non-Coding RNAs.
LF382962 - JP 2014500723-A/190465: Polycomb-Associated Non-Coding RNAs.
LF382959 - JP 2014500723-A/190462: Polycomb-Associated Non-Coding RNAs.
LF382958 - JP 2014500723-A/190461: Polycomb-Associated Non-Coding RNAs.
MA618541 - JP 2018138019-A/190467: Polycomb-Associated Non-Coding RNAs.
MA618539 - JP 2018138019-A/190465: Polycomb-Associated Non-Coding RNAs.
MA618536 - JP 2018138019-A/190462: Polycomb-Associated Non-Coding RNAs.
MA618535 - JP 2018138019-A/190461: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: B7Z2J8, B7Z3S7, B9EGC7, C9JMA4, C9JYW0, ENST00000379643.1, ENST00000379643.2, ENST00000379643.3, ENST00000379643.4, ENST00000379643.5, ENST00000379643.6, ENST00000379643.7, ENST00000379643.8, ENST00000379643.9, MA7D2_HUMAN, NM_001168465, Q5EBN1, Q5JPS7, Q6PIC7, Q8N792, Q96T17, uc318pcg.1, uc318pcg.2
UCSC ID: ENST00000379643.10_11
RefSeq Accession: NM_001168465.2
Protein: Q96T17 (aka MA7D2_HUMAN)

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.