Human Gene MDM1 (ENST00000682720.1_4) from GENCODE V47lift37
  Description: Mdm1 nuclear protein, transcript variant 5 (from RefSeq NM_001354969.2)
Gencode Transcript: ENST00000682720.1_4
Gencode Gene: ENSG00000111554.15_12
Transcript (Including UTRs)
   Position: hg19 chr12:68,688,346-68,726,142 Size: 37,797 Total Exon Count: 15 Strand: -
Coding Region
   Position: hg19 chr12:68,689,034-68,726,025 Size: 36,992 Coding Exon Count: 15 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:68,688,346-68,726,142)mRNA (may differ from genome)Protein (724 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: MDM1
Diseases sorted by gene-association score: retinitis pigmentosa 3 (6)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -43.70117-0.374 Picture PostScript Text
3' UTR -125.50688-0.182 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  KJ899258 - Synthetic construct Homo sapiens clone ccsbBroadEn_08652 MDM1 gene, encodes complete protein.
KJ902913 - Synthetic construct Homo sapiens clone ccsbBroadEn_12307 MDM1 gene, encodes complete protein.
LF208897 - JP 2014500723-A/16400: Polycomb-Associated Non-Coding RNAs.
AK026745 - Homo sapiens cDNA: FLJ23092 fis, clone LNG07245, highly similar to AF007130 Homo sapiens clone 23750 unknown mRNA.
BC028355 - Homo sapiens Mdm1 nuclear protein homolog (mouse), mRNA (cDNA clone MGC:26064 IMAGE:4827410), complete cds.
AF007130 - Homo sapiens clone 23750 unknown mRNA, partial cds.
BC034945 - Homo sapiens Mdm4, transformed 3T3 cell double minute 1, p53 binding protein (mouse), mRNA (cDNA clone IMAGE:4821794).
JD289735 - Sequence 270759 from Patent EP1572962.
AK297311 - Homo sapiens cDNA FLJ58512 complete cds, highly similar to Homo sapiens Mdm4, transformed 3T3 cell double minute 1, p53 binding protein, transcript variant 1, mRNA.
LF323874 - JP 2014500723-A/131377: Polycomb-Associated Non-Coding RNAs.
LF323873 - JP 2014500723-A/131376: Polycomb-Associated Non-Coding RNAs.
CQ873868 - Sequence 287 from Patent WO2004076622.
DD413705 - Regulation of Mammalian Cells.
LF323872 - JP 2014500723-A/131375: Polycomb-Associated Non-Coding RNAs.
BC010622 - Homo sapiens Mdm4, transformed 3T3 cell double minute 1, p53 binding protein (mouse), mRNA (cDNA clone IMAGE:3874354), with apparent retained intron.
AF267851 - Homo sapiens nuclear protein double minute 1 mRNA, complete cds.
JD117965 - Sequence 98989 from Patent EP1572962.
JD562406 - Sequence 543430 from Patent EP1572962.
JD428584 - Sequence 409608 from Patent EP1572962.
AK314461 - Homo sapiens cDNA, FLJ95264, highly similar to Homo sapiens Mdm4, transformed 3T3 cell double minute 1, p53 binding protein (mouse) (MDM1), transcript variant 2, mRNA.
BC022042 - Homo sapiens Mdm1 nuclear protein homolog (mouse), mRNA (cDNA clone IMAGE:4670016), complete cds.
JD152061 - Sequence 133085 from Patent EP1572962.
JD405751 - Sequence 386775 from Patent EP1572962.
MA559451 - JP 2018138019-A/131377: Polycomb-Associated Non-Coding RNAs.
MA559450 - JP 2018138019-A/131376: Polycomb-Associated Non-Coding RNAs.
MA559449 - JP 2018138019-A/131375: Polycomb-Associated Non-Coding RNAs.
MA444474 - JP 2018138019-A/16400: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A804HIJ5, A0A804HIJ5_HUMAN, MDM1 , NM_001354969, uc330kik.1, uc330kik.2
UCSC ID: ENST00000682720.1_4
RefSeq Accession: NM_001354969.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.