The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P52815
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
X79865 - H.sapiens Mrp17 mRNA. AK297076 - Homo sapiens cDNA FLJ60124 complete cds, highly similar to Mitochondrial dicarboxylate carrier. BC002344 - Homo sapiens mitochondrial ribosomal protein L12, mRNA (cDNA clone MGC:8610 IMAGE:2961288), complete cds. JD497536 - Sequence 478560 from Patent EP1572962. BC007497 - Homo sapiens mitochondrial ribosomal protein L12, mRNA (cDNA clone MGC:3660 IMAGE:2959986), complete cds. U25041 - Homo sapiens 5C5 mRNA, complete cds. EF036488 - Homo sapiens mitochondrial ribosomal protein L12 mRNA, partial cds; nuclear gene for mitochondrial product. KJ892049 - Synthetic construct Homo sapiens clone ccsbBroadEn_01443 MRPL12 gene, encodes complete protein. AF105278 - Homo sapiens 5c5-2 protein mRNA, complete cds. JD021541 - Sequence 2565 from Patent EP1572962. JD034984 - Sequence 16008 from Patent EP1572962. JD472998 - Sequence 454022 from Patent EP1572962. JD396278 - Sequence 377302 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein P52815 (Reactome details) participates in the following event(s):
R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA R-HSA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA R-HSA-5368286 Mitochondrial translation initiation R-HSA-5419276 Mitochondrial translation termination R-HSA-5368287 Mitochondrial translation R-HSA-5389840 Mitochondrial translation elongation R-HSA-72766 Translation R-HSA-392499 Metabolism of proteins
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
