The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8N5N7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
BC015133 - Homo sapiens cDNA clone IMAGE:3934193, partial cds. AK295521 - Homo sapiens cDNA FLJ52265 complete cds, highly similar to Homo sapiens mitochondrial ribosomal protein L50 (MRPL50), mRNA. AK025643 - Homo sapiens cDNA: FLJ21990 fis, clone HEP06386. AK000500 - Homo sapiens cDNA FLJ20493 fis, clone KAT08512. BC032008 - Homo sapiens mitochondrial ribosomal protein L50, mRNA (cDNA clone MGC:21150 IMAGE:4749199), complete cds. JD438721 - Sequence 419745 from Patent EP1572962. JD494873 - Sequence 475897 from Patent EP1572962. JF432491 - Synthetic construct Homo sapiens clone IMAGE:100073712 mitochondrial ribosomal protein L50 (MRPL50) gene, encodes complete protein. KJ898997 - Synthetic construct Homo sapiens clone ccsbBroadEn_08391 MRPL50 gene, encodes complete protein.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q8N5N7 (Reactome details) participates in the following event(s):
R-HSA-5389839 39S subunit binds 28S subunit:mRNA:fMet-tRNA R-HSA-5419273 Hydrolysis of GTP and dissociation of 28S and 39S subunits R-HSA-5389848 TUFM:GTP:aminoacyl-tRNA binds 55S ribosome:mRNA:fMet-tRNA R-HSA-5389857 Peptide transfer from P-site to A-site (peptide bond formation) R-HSA-5389842 TUFM hydrolyzes GTP and TUFM:GDP dissociates from 55S ribosome R-HSA-5419261 55S ribosome with peptidyl-tRNA in A site binds GFM1:GTP R-HSA-5419281 MRRF binds 55S ribosome:mRNA:tRNA R-HSA-5419279 Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA) R-HSA-5419264 MTRF1L (MTRF1a) or ICT1 binds stop codon in 55S ribosome:mRNA:peptidyl-tRNA R-HSA-5419277 GFM2:GTP binds 55S ribosome:mRNA:tRNA:MRRF releasing mRNA and tRNA R-HSA-5368286 Mitochondrial translation initiation R-HSA-5419276 Mitochondrial translation termination R-HSA-5368287 Mitochondrial translation R-HSA-5389840 Mitochondrial translation elongation R-HSA-72766 Translation R-HSA-392499 Metabolism of proteins
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
