Human Gene MRPS14 (ENST00000476371.1_7) from GENCODE V47lift37

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Description: mitochondrial ribosomal protein S14, transcript variant 2 (from RefSeq NR_037606.2)
Gencode Transcript: ENST00000476371.1_7
Gencode Gene: ENSG00000120333.4_9
Transcript (Including UTRs)
Position: hg19 chr1:174,982,094-174,992,561 Size: 10,468 Total Exon Count: 3 Strand: -
Coding Region
Position: hg19 chr1:174,983,805-174,992,544 Size: 8,740 Coding Exon Count: 3

Page Index	Sequence and Links	Primers	CTD	Gene Alleles	RNA-Seq Expression
Microarray Expression	RNA Structure	Protein Structure	Other Species	GO Annotations	mRNA Descriptions
Other Names	Model Information	Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr1:174,982,094-174,992,561)			mRNA (may differ from genome)		Protein (128 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	Entrez Gene	ExonPrimer	GeneCards
HGNC	MGI	OMIM	PubMed	UniProtKB	BioGrid CRISPR DB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene C006780 bisphenol A C016403 2,4-dinitrotoluene C023514 2,6-dinitrotoluene C030370 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone D000082 Acetaminophen D019327 Copper Sulfate D006861 Hydrogen Peroxide D011285 Pregnenolone Carbonitrile D012999 Soman C018021 cobaltous chloride more ... click here to view the complete list

Common Gene Haplotype Alleles


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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)


	Highest median expression: 15.93 RPKM in Brain - Spinal cord (cervical c-1) Total median expression: 601.78 RPKM View in GTEx track of Genome Browser View at GTEx portal View GTEx Body Map

Microarray Expression Data


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mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-1.50	17	-0.088	Picture	PostScript	Text
3' UTR	-410.40	1711	-0.240	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Protein Domain and Structure Information

InterPro Domains: Graphical view of domain structure
IPR001209 - Ribosomal_S14

Pfam Domains:
PF00253 - Ribosomal protein S14p/S29e

SCOP Domains:
57716 - Glucocorticoid receptor-like (DNA-binding domain)

ModBase Predicted Comparative 3D Structure on Q96Q61


Front	Top	Side

The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	Genome Browser	Genome Browser
Gene Details	Gene Details		Gene Details	Gene Details	Gene Details
Gene Sorter	Gene Sorter		Gene Sorter	Gene Sorter	Gene Sorter
	RGD	Ensembl		WormBase	SGD
				Protein Sequence	Protein Sequence
				Alignment	Alignment

Gene Ontology (GO) Annotations with Structured Vocabulary


	Cellular Component: GO:0005840 ribosome

Descriptions from all associated GenBank mRNAs


	LF383649 - JP 2014500723-A/191152: Polycomb-Associated Non-Coding RNAs. AL049705 - Human gene from PAC 262D12, chromosome 1. AK310915 - Homo sapiens cDNA, FLJ17957. JD475482 - Sequence 456506 from Patent EP1572962. JD447532 - Sequence 428556 from Patent EP1572962. JD360454 - Sequence 341478 from Patent EP1572962. LF320230 - JP 2014500723-A/127733: Polycomb-Associated Non-Coding RNAs. JD553072 - Sequence 534096 from Patent EP1572962. LF318789 - JP 2014500723-A/126292: Polycomb-Associated Non-Coding RNAs. LF205268 - JP 2014500723-A/12771: Polycomb-Associated Non-Coding RNAs. JD283986 - Sequence 265010 from Patent EP1572962. BC009788 - Homo sapiens mitochondrial ribosomal protein S14, mRNA (cDNA clone MGC:13571 IMAGE:4132323), complete cds. JD410937 - Sequence 391961 from Patent EP1572962. LF320229 - JP 2014500723-A/127732: Polycomb-Associated Non-Coding RNAs. JD381999 - Sequence 363023 from Patent EP1572962. JD425194 - Sequence 406218 from Patent EP1572962. AK311759 - Homo sapiens cDNA, FLJ92019, highly similar to Homo sapiens mitochondrial ribosomal protein S14 (MRPS14), nuclear gene encoding mitochondrial protein, mRNA. KJ894515 - Synthetic construct Homo sapiens clone ccsbBroadEn_03909 MRPS14 gene, encodes complete protein. LF320226 - JP 2014500723-A/127729: Polycomb-Associated Non-Coding RNAs. LF318790 - JP 2014500723-A/126293: Polycomb-Associated Non-Coding RNAs. MA619226 - JP 2018138019-A/191152: Polycomb-Associated Non-Coding RNAs. MA555807 - JP 2018138019-A/127733: Polycomb-Associated Non-Coding RNAs. MA554366 - JP 2018138019-A/126292: Polycomb-Associated Non-Coding RNAs. MA440845 - JP 2018138019-A/12771: Polycomb-Associated Non-Coding RNAs. MA555806 - JP 2018138019-A/127732: Polycomb-Associated Non-Coding RNAs. MA555803 - JP 2018138019-A/127729: Polycomb-Associated Non-Coding RNAs. MA554367 - JP 2018138019-A/126293: Polycomb-Associated Non-Coding RNAs.

Other Names for This Gene


	Alternate Gene Symbols: MRPS14 , NR_037606, Q96Q61, Q96Q61_HUMAN, uc321umz.1, uc321umz.2 UCSC ID: ENST00000476371.1_7 RefSeq Accession: NM_022100.3 Protein: Q96Q61

Gene Model Information


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Methods, Credits, and Use Restrictions


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