Human Gene MSN (ENST00000360270.7_5) from GENCODE V47lift37
  Description: moesin (from RefSeq NM_002444.3)
Gencode Transcript: ENST00000360270.7_5
Gencode Gene: ENSG00000147065.18_11
Transcript (Including UTRs)
   Position: hg19 chrX:64,887,521-64,961,793 Size: 74,273 Total Exon Count: 13 Strand: +
Coding Region
   Position: hg19 chrX:64,887,709-64,959,755 Size: 72,047 Coding Exon Count: 13 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:64,887,521-64,961,793)mRNA (may differ from genome)Protein (577 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMalacardsMGIOMIMPubMedUniProtKB
WikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: MSN
Diseases sorted by gene-association score: immunodeficiency 50* (1228), verrucous carcinoma (27), neurofibromatosis, type 2 (17), measles (9), robinow syndrome, autosomal dominant 1 (8), neisseria meningitidis infection (7), neurilemmoma (6), deafness, autosomal recessive 24 (6), meningioma, familial (5), schwannomatosis (4)
* = Manually curated disease association

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 151.80 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 2780.13 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -60.90188-0.324 Picture PostScript Text
3' UTR -569.602038-0.279 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details Gene Details  
Gene SorterGene Sorter Gene Sorter  
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  BC001112 - Homo sapiens moesin, mRNA (cDNA clone IMAGE:2967515), partial cds.
BC011827 - Homo sapiens moesin, mRNA (cDNA clone IMAGE:3832468), partial cds.
BC017293 - Homo sapiens moesin, mRNA (cDNA clone MGC:29549 IMAGE:4908580), complete cds.
EU794636 - Homo sapiens epididymis luminal protein 70 (HEL70) mRNA, complete cds.
AK309986 - Homo sapiens cDNA, FLJ17028.
M69066 - Human moesin mRNA, complete cds.
AF295356 - Homo sapiens moesin/anaplastic lymphoma kinase fusion protein (MSN/ALK fusion) mRNA, partial cds.
DQ895892 - Synthetic construct Homo sapiens clone IMAGE:100010352; FLH188674.01L; RZPDo839E1163D moesin (MSN) gene, encodes complete protein.
DQ892653 - Synthetic construct clone IMAGE:100005283; FLH188678.01X; RZPDo839E1173D moesin (MSN) gene, encodes complete protein.
AK308486 - Homo sapiens cDNA, FLJ98527.
AB527296 - Synthetic construct DNA, clone: pF1KB3466, Homo sapiens MSN gene for moesin, without stop codon, in Flexi system.
KJ904508 - Synthetic construct Homo sapiens clone ccsbBroadEn_13902 MSN gene, encodes complete protein.
AK309354 - Homo sapiens cDNA, FLJ99395.
AK297165 - Homo sapiens cDNA FLJ57321 complete cds, moderately similar to Moesin.
JD452861 - Sequence 433885 from Patent EP1572962.
JD314065 - Sequence 295089 from Patent EP1572962.
JD474409 - Sequence 455433 from Patent EP1572962.
JD070680 - Sequence 51704 from Patent EP1572962.
JD121334 - Sequence 102358 from Patent EP1572962.
JD314206 - Sequence 295230 from Patent EP1572962.
JD190903 - Sequence 171927 from Patent EP1572962.
JD243924 - Sequence 224948 from Patent EP1572962.
JD170034 - Sequence 151058 from Patent EP1572962.
JD281088 - Sequence 262112 from Patent EP1572962.
JD171367 - Sequence 152391 from Patent EP1572962.
JD149224 - Sequence 130248 from Patent EP1572962.
JD559890 - Sequence 540914 from Patent EP1572962.
JD310675 - Sequence 291699 from Patent EP1572962.
JD338025 - Sequence 319049 from Patent EP1572962.
JD253567 - Sequence 234591 from Patent EP1572962.
JD391845 - Sequence 372869 from Patent EP1572962.
JD350045 - Sequence 331069 from Patent EP1572962.
JD549687 - Sequence 530711 from Patent EP1572962.
JD375140 - Sequence 356164 from Patent EP1572962.
JD110274 - Sequence 91298 from Patent EP1572962.
JD170548 - Sequence 151572 from Patent EP1572962.
JD418014 - Sequence 399038 from Patent EP1572962.
JD164437 - Sequence 145461 from Patent EP1572962.
JD339334 - Sequence 320358 from Patent EP1572962.
JD259831 - Sequence 240855 from Patent EP1572962.
JD145443 - Sequence 126467 from Patent EP1572962.
JD278002 - Sequence 259026 from Patent EP1572962.
JD148838 - Sequence 129862 from Patent EP1572962.
DL492399 - Novel nucleic acids.
DL490882 - Novel nucleic acids.
JD316086 - Sequence 297110 from Patent EP1572962.
JD321005 - Sequence 302029 from Patent EP1572962.
JD339759 - Sequence 320783 from Patent EP1572962.
JD177305 - Sequence 158329 from Patent EP1572962.
JD290415 - Sequence 271439 from Patent EP1572962.
JD233098 - Sequence 214122 from Patent EP1572962.
JD503019 - Sequence 484043 from Patent EP1572962.
JD304697 - Sequence 285721 from Patent EP1572962.
JD509172 - Sequence 490196 from Patent EP1572962.
JD428714 - Sequence 409738 from Patent EP1572962.
JD193610 - Sequence 174634 from Patent EP1572962.
L32785 - Homo sapiens (isolate XP14C1B) moesin mRNA, partial EST.
JD269165 - Sequence 250189 from Patent EP1572962.
JD429544 - Sequence 410568 from Patent EP1572962.
JD235379 - Sequence 216403 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000360270.1, ENST00000360270.2, ENST00000360270.3, ENST00000360270.4, ENST00000360270.5, ENST00000360270.6, hCG_18939 , HEL70 , MSN , NM_002444, uc318bls.1, uc318bls.2, V9HWC0, V9HWC0_HUMAN
UCSC ID: ENST00000360270.7_5
RefSeq Accession: NM_002444.3

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.