ID:NUPR1_HUMAN DESCRIPTION: RecName: Full=Nuclear protein 1; AltName: Full=Candidate of metastasis 1; AltName: Full=Protein p8; FUNCTION: Could participate in the response to proapoptotic stimuli and promotes cellular growth in a way that helps the tissue counteract diverse injuries. May contribute to the metastatic phenotype. SUBCELLULAR LOCATION: Nucleus. TISSUE SPECIFICITY: Highly expressed in pancreas. PTM: Phosphorylated. SIMILARITY: Belongs to the NUPR family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O60356
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0002526 acute inflammatory response GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0006473 protein acetylation GO:0008283 cell proliferation GO:0008584 male gonad development GO:0009636 response to toxic substance GO:0031401 positive regulation of protein modification process GO:0035914 skeletal muscle cell differentiation GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0043065 positive regulation of apoptotic process GO:0045786 negative regulation of cell cycle GO:0048147 negative regulation of fibroblast proliferation GO:0065003 macromolecular complex assembly GO:2000194 regulation of female gonad development
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
