ID:PCP4_HUMAN DESCRIPTION: RecName: Full=Purkinje cell protein 4; AltName: Full=Brain-specific antigen PCP-4; AltName: Full=Brain-specific polypeptide PEP-19; FUNCTION: Probable regulator of calmodulin signaling. SUBUNIT: Binds to both calcium-free and calcium activated calmodulin, affinity for calcium-bound form is 50-fold greater. DOMAIN: Mostly intrisically disordered, with residual structure localized to the IQ motif (PubMed:19106096). SIMILARITY: Belongs to the PCP4 family. SIMILARITY: Contains 1 IQ domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00612 - IQ calmodulin-binding motif
ModBase Predicted Comparative 3D Structure on P48539
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.