ID:PEF1_HUMAN DESCRIPTION: RecName: Full=Peflin; AltName: Full=PEF protein with a long N-terminal hydrophobic domain; AltName: Full=Penta-EF hand domain-containing protein 1; SUBUNIT: Heterodimer; heterodimerizes with PDCD6. Dissociates from PDCD6 in presence of Ca(2+). INTERACTION: Q15038:DAZAP2; NbExp=3; IntAct=EBI-724639, EBI-724310; Q53G59:KLHL12; NbExp=2; IntAct=EBI-724639, EBI-740929; SUBCELLULAR LOCATION: Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated in the presence of Ca(2+). SIMILARITY: Contains 5 EF-hand domains.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9UBV8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006508 proteolysis GO:0006888 ER to Golgi vesicle-mediated transport GO:0014029 neural crest formation GO:0014032 neural crest cell development GO:0048208 COPII vesicle coating GO:0051592 response to calcium ion GO:1902527 positive regulation of protein monoubiquitination
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
