The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q53XY6
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0008083 growth factor activity GO:0042803 protein homodimerization activity GO:0046982 protein heterodimerization activity
Biological Process: GO:0001658 branching involved in ureteric bud morphogenesis GO:0001666 response to hypoxia GO:0001938 positive regulation of endothelial cell proliferation GO:0002040 sprouting angiogenesis GO:0007565 female pregnancy GO:0010469 regulation of receptor activity GO:0031100 animal organ regeneration GO:0032870 cellular response to hormone stimulus GO:0042493 response to drug GO:0045766 positive regulation of angiogenesis GO:0060688 regulation of morphogenesis of a branching structure
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
