ID:POC5_HUMAN DESCRIPTION: RecName: Full=Centrosomal protein POC5; AltName: Full=Protein of centriole 5; Short=hPOC5; FUNCTION: Essential for the assembly of the distal half of centrioles, required for centriole elongation. SUBUNIT: Interacts with CETN2 and CETN3. SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, centrosome, centriole. Note=Localized to the distal portion of centrioles. PTM: Hyperphosphorylated during recruitment to procentrioles in G2/M phase. SIMILARITY: Belongs to the POC5 family. SEQUENCE CAUTION: Sequence=BC101328; Type=Frameshift; Positions=195;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8NA72
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.