The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9BT43
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK092209 - Homo sapiens cDNA FLJ34890 fis, clone NT2NE2017508. AK056984 - Homo sapiens cDNA FLJ32422 fis, clone SKMUS2000933, weakly similar to RNA polymerase III subunit. BC004355 - Homo sapiens polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like, mRNA (cDNA clone MGC:3200 IMAGE:3357827), complete cds. LF383817 - JP 2014500723-A/191320: Polycomb-Associated Non-Coding RNAs. BC050418 - Homo sapiens polymerase (RNA) III (DNA directed) polypeptide G (32kD) like, mRNA (cDNA clone IMAGE:5588819). JD220546 - Sequence 201570 from Patent EP1572962. JD566058 - Sequence 547082 from Patent EP1572962. JD176206 - Sequence 157230 from Patent EP1572962. JD026253 - Sequence 7277 from Patent EP1572962. LF352657 - JP 2014500723-A/160160: Polycomb-Associated Non-Coding RNAs. DQ418461 - Homo sapiens alternative RNA polymerase III subunit 32 mRNA, complete cds. KJ894956 - Synthetic construct Homo sapiens clone ccsbBroadEn_04350 POLR3GL gene, encodes complete protein. LF352658 - JP 2014500723-A/160161: Polycomb-Associated Non-Coding RNAs. CU678682 - Synthetic construct Homo sapiens gateway clone IMAGE:100017611 5' read POLR3GL mRNA. JD118898 - Sequence 99922 from Patent EP1572962. JD218057 - Sequence 199081 from Patent EP1572962. JD487856 - Sequence 468880 from Patent EP1572962. MA619394 - JP 2018138019-A/191320: Polycomb-Associated Non-Coding RNAs. MA588234 - JP 2018138019-A/160160: Polycomb-Associated Non-Coding RNAs. MA588235 - JP 2018138019-A/160161: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q9BT43 (Reactome details) participates in the following event(s):
R-HSA-76056 Recruitment of RNA polymerase III to TFIIIB:TFIIIC:TFIIIA:Type 1 Promoter Complex R-HSA-83803 Recruitment of RNA Polymerase III to TFIIIB:SNAPc:Type 3 Promoter Complex R-HSA-83805 Recruitment of RNA Polymerase III to the TFIIIB:TFIIIC: Type 2 Promoter Complex R-HSA-113454 RNA Polymerase III Termination and release of transcribed RNA R-HSA-76060 RNA Polymerase III Promoter Opening at Type 1 Promoters R-HSA-112150 RNA Polymerase III Promoter Opening at Type 2 Promoters R-HSA-112152 RNA Polymerase III Promoter Opening at Type 3 Promoters R-HSA-112055 RNA Polymerase III Abortive Initiation At Type 1 Open Promoters R-HSA-112153 RNA Polymerase III Simple Start Sequence Initiation At Type 1 Promoters R-HSA-112149 RNA Polymerase III Abortive Initiation At Type 2 Open Promoters R-HSA-112155 RNA Polymerase III Simple Start Sequence Initiation At Type 2 Promoters R-HSA-112054 RNA Polymerase III Abortive Initiation At Type 3 Open Promoters R-HSA-112156 RNA Polymerase III Simple Start Sequence Initiation At Type 3 Promoters R-HSA-113442 RNA Polymerase III Retractive RNase Activity at U-tract Pause Sites R-HSA-113446 Initiation of RNA Polymerase III Productive Transcription R-HSA-113449 RNA Polymerase III Transcriptional Pause at Terminator Sequence R-HSA-113451 Resumption of RNA Polymerase III Productive Transcription R-HSA-113705 RNA Polymerase III Productive Transcription R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter R-HSA-73980 RNA Polymerase III Transcription Termination R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation R-HSA-73780 RNA Polymerase III Chain Elongation R-HSA-76046 RNA Polymerase III Transcription Initiation R-HSA-74158 RNA Polymerase III Transcription R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA R-HSA-74160 Gene expression (Transcription) R-HSA-168249 Innate Immune System R-HSA-168256 Immune System