Human Gene POU2F2 (ENST00000692977.1_6) from GENCODE V47lift37

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Description: POU class 2 homeobox 2, transcript variant 8 (from RefSeq NM_001394376.1)
Gencode Transcript: ENST00000692977.1_6
Gencode Gene: ENSG00000028277.22_18
Transcript (Including UTRs)
Position: hg19 chr19:42,590,262-42,636,598 Size: 46,337 Total Exon Count: 15 Strand: -
Coding Region
Position: hg19 chr19:42,595,409-42,636,563 Size: 41,155 Coding Exon Count: 15

Page Index	Sequence and Links	Primers	MalaCards	CTD	Gene Alleles
Microarray Expression	RNA Structure	Other Species	mRNA Descriptions	Other Names	Model Information
Methods

Data last updated at UCSC: 2024-08-22 23:36:26

Sequence and Links to Tools and Databases

Genomic Sequence (chr19:42,590,262-42,636,598)			mRNA (may differ from genome)		Protein (624 aa)
Gene Sorter	Genome Browser	Other Species FASTA	VisiGene	Gene interactions	Table Schema
AlphaFold	BioGPS	Ensembl	ExonPrimer	GeneCards	HGNC
Malacards	MGI	PubMed	UniProtKB

Primer design for this transcript

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3

MalaCards Disease Associations


	MalaCards Gene Search: POU2F2 Diseases sorted by gene-association score: papilloma (3), t-cell/histiocyte rich large b cell lymphoma (3)

Comparative Toxicogenomics Database (CTD)


	The following chemicals interact with this gene C479799 (E)-4-((2-N-(4-methoxybenzenesulfonyl)amino)stilbazole)1-oxide C027576 4-hydroxy-2-nonenal D000643 Ammonium Chloride D002794 Choline D005492 Folic Acid D015759 Ionomycin D007854 Lead D058185 Magnetite Nanoparticles D008715 Methionine C568608 PCI 5002 D010795 Phthalic Acids C513635 S-2-pentyl-4-pentynoic hydroxamic acid D004113 Succimer D013755 Tetradecanoylphorbol Acetate D014635 Valproic Acid D015032 Zinc C400082 bortezomib C008261 lead acetate C484027 oligofectamine C020972 pyrrolidine dithiocarbamic acid C017947 sodium arsenite C015559 trimellitic anhydride

Common Gene Haplotype Alleles


	Press "+" in the title bar above to open this section.

Microarray Expression Data


	Press "+" in the title bar above to open this section.

mRNA Secondary Structure of 3' and 5' UTRs

Region	Fold Energy	Bases	Energy/Base	Display As
5' UTR	-16.70	35	-0.477	Picture	PostScript	Text
3' UTR	-1883.80	5147	-0.366	Picture	PostScript	Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

Orthologous Genes in Other Species

Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.

Mouse	Rat	Zebrafish	D. melanogaster	C. elegans	S. cerevisiae
No ortholog	No ortholog	No ortholog	No ortholog	No ortholog	No ortholog
Gene Details	Gene Details
Gene Sorter	Gene Sorter
	RGD

Descriptions from all associated GenBank mRNAs


	M36542 - Human lymphoid-specific transcription factor mRNA, complete cds. X13810 - Human OTF-2 mRNA for lymphoid-specific transcription factor. M36718 - Human octamer-binding transcription factor (OTF2) mRNA, 3' end. X13809 - Human OTF-2 mRNA for lymphocyte-specific transcription factor. BC006101 - Homo sapiens POU class 2 homeobox 2, mRNA (cDNA clone MGC:12814 IMAGE:3688152), complete cds. AB590941 - Synthetic construct DNA, clone: pFN21AB9439, Homo sapiens POU2F2 gene for POU class 2 homeobox 2, without stop codon, in Flexi system. M36653 - Human Oct-2 factor mRNA, complete cds. X53468 - Human oct-2 mRNA for B-cell specific transcription factor NF-A2. KJ901653 - Synthetic construct Homo sapiens clone ccsbBroadEn_11047 POU2F2 gene, encodes complete protein. BT007438 - Homo sapiens POU domain, class 2, transcription factor 2 mRNA, complete cds. M22596 - Homo sapiens homeobox protein (oct-2) mRNA, partial cds. LF207557 - JP 2014500723-A/15060: Polycomb-Associated Non-Coding RNAs. JD370879 - Sequence 351903 from Patent EP1572962. JD436098 - Sequence 417122 from Patent EP1572962. JD104272 - Sequence 85296 from Patent EP1572962. JD294417 - Sequence 275441 from Patent EP1572962. JD158478 - Sequence 139502 from Patent EP1572962. JD495102 - Sequence 476126 from Patent EP1572962. JD092150 - Sequence 73174 from Patent EP1572962. JD121772 - Sequence 102796 from Patent EP1572962. JD469947 - Sequence 450971 from Patent EP1572962. JD218734 - Sequence 199758 from Patent EP1572962. JD441572 - Sequence 422596 from Patent EP1572962. LF367074 - JP 2014500723-A/174577: Polycomb-Associated Non-Coding RNAs. JD243747 - Sequence 224771 from Patent EP1572962. JD263694 - Sequence 244718 from Patent EP1572962. JD525767 - Sequence 506791 from Patent EP1572962. JD132734 - Sequence 113758 from Patent EP1572962. JD418560 - Sequence 399584 from Patent EP1572962. JD555625 - Sequence 536649 from Patent EP1572962. JD521536 - Sequence 502560 from Patent EP1572962. JD418761 - Sequence 399785 from Patent EP1572962. JD132835 - Sequence 113859 from Patent EP1572962. JD254315 - Sequence 235339 from Patent EP1572962. JD402474 - Sequence 383498 from Patent EP1572962. JD521535 - Sequence 502559 from Patent EP1572962. JD418760 - Sequence 399784 from Patent EP1572962. JD132834 - Sequence 113858 from Patent EP1572962. JD322209 - Sequence 303233 from Patent EP1572962. JD420442 - Sequence 401466 from Patent EP1572962. JD260200 - Sequence 241224 from Patent EP1572962. JD259998 - Sequence 241022 from Patent EP1572962. JD257370 - Sequence 238394 from Patent EP1572962. JD217713 - Sequence 198737 from Patent EP1572962. JD498548 - Sequence 479572 from Patent EP1572962. JD547271 - Sequence 528295 from Patent EP1572962. JD364688 - Sequence 345712 from Patent EP1572962. JD554276 - Sequence 535300 from Patent EP1572962. JD043901 - Sequence 24925 from Patent EP1572962. JD263078 - Sequence 244102 from Patent EP1572962. JD218611 - Sequence 199635 from Patent EP1572962. JD449957 - Sequence 430981 from Patent EP1572962. JD483178 - Sequence 464202 from Patent EP1572962. JD482900 - Sequence 463924 from Patent EP1572962. JD071538 - Sequence 52562 from Patent EP1572962. JD186454 - Sequence 167478 from Patent EP1572962. JD203536 - Sequence 184560 from Patent EP1572962. M36772 - Human Oct-2 factor mRNA, 3' end. X53469 - Human oct-2 mRNA for B-cell specific transcription factor NF-A2, part. with different C-term. JD104234 - Sequence 85258 from Patent EP1572962. JD327020 - Sequence 308044 from Patent EP1572962. JD253806 - Sequence 234830 from Patent EP1572962. JD249156 - Sequence 230180 from Patent EP1572962. JD528695 - Sequence 509719 from Patent EP1572962. JD153860 - Sequence 134884 from Patent EP1572962. JD159474 - Sequence 140498 from Patent EP1572962. JD497045 - Sequence 478069 from Patent EP1572962. JD124895 - Sequence 105919 from Patent EP1572962. JD322111 - Sequence 303135 from Patent EP1572962. JD523200 - Sequence 504224 from Patent EP1572962. JD477545 - Sequence 458569 from Patent EP1572962. JD055744 - Sequence 36768 from Patent EP1572962. MA602651 - JP 2018138019-A/174577: Polycomb-Associated Non-Coding RNAs. MA443134 - JP 2018138019-A/15060: Polycomb-Associated Non-Coding RNAs. JD186960 - Sequence 167984 from Patent EP1572962. JD483219 - Sequence 464243 from Patent EP1572962. JD408327 - Sequence 389351 from Patent EP1572962. JD462946 - Sequence 443970 from Patent EP1572962.

Other Names for This Gene


	Alternate Gene Symbols: A0A8I5KYI8, A0A8I5KYI8_HUMAN, NM_001394376, POU2F2 , uc330xyt.1, uc330xyt.2 UCSC ID: ENST00000692977.1_6 RefSeq Accession: NM_001394376.1

Gene Model Information


	Click here for a detailed description of the fields of the table above.

Methods, Credits, and Use Restrictions


	Click here for details on how this gene model was made and data restrictions if any.