ID:SSF1_HUMAN DESCRIPTION: RecName: Full=Suppressor of SWI4 1 homolog; Short=Ssf-1; AltName: Full=Brix domain-containing protein 3; AltName: Full=Peter Pan homolog; FUNCTION: May have a role in cell growth. SUBCELLULAR LOCATION: Nucleus, nucleolus. TISSUE SPECIFICITY: Widely expressed. MISCELLANEOUS: A chimeric transcript, characterized by the first third of PPAN exon 12 joined to P2RY11 exon 2, has been detected. It is possibly produced by trans-splicing. The chimeric transcript is widely expressed and can be induced by retinoic acid during the granulocytic differentiation of the HL60 cell line. The resulting chimeric protein shows a much lower activity than the non-chimeric P2RY11 gene product, but qualitatively indistinguishable (PubMed:11278528). SIMILARITY: Contains 1 Brix domain.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NQ55
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.