The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P30405
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0000413 protein peptidyl-prolyl isomerization GO:0002931 response to ischemia GO:0006457 protein folding GO:0006915 apoptotic process GO:0006979 response to oxidative stress GO:0008637 apoptotic mitochondrial changes GO:0010849 regulation of proton-transporting ATPase activity, rotational mechanism GO:0010939 regulation of necrotic cell death GO:0012501 programmed cell death GO:0032780 negative regulation of ATPase activity GO:0042981 regulation of apoptotic process GO:0043066 negative regulation of apoptotic process GO:0046902 regulation of mitochondrial membrane permeability GO:0070266 necroptotic process GO:0070301 cellular response to hydrogen peroxide GO:0071243 cellular response to arsenic-containing substance GO:0071277 cellular response to calcium ion GO:0090200 positive regulation of release of cytochrome c from mitochondria GO:0090201 negative regulation of release of cytochrome c from mitochondria GO:0090324 negative regulation of oxidative phosphorylation GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity GO:2001243 negative regulation of intrinsic apoptotic signaling pathway