The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P30044
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0001016 RNA polymerase III regulatory region DNA binding GO:0004601 peroxidase activity GO:0005102 receptor binding GO:0008379 thioredoxin peroxidase activity GO:0016209 antioxidant activity GO:0016491 oxidoreductase activity GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process GO:0046983 protein dimerization activity GO:0051920 peroxiredoxin activity GO:0072541 peroxynitrite reductase activity
Biological Process: GO:0006915 apoptotic process GO:0006954 inflammatory response GO:0006979 response to oxidative stress GO:0016480 negative regulation of transcription from RNA polymerase III promoter GO:0032967 positive regulation of collagen biosynthetic process GO:0034599 cellular response to oxidative stress GO:0034614 cellular response to reactive oxygen species GO:0042744 hydrogen peroxide catabolic process GO:0043066 negative regulation of apoptotic process GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0045454 cell redox homeostasis GO:0051354 negative regulation of oxidoreductase activity GO:0055114 oxidation-reduction process GO:0060785 regulation of apoptosis involved in tissue homeostasis GO:0070995 NADPH oxidation GO:0098869 cellular oxidant detoxification GO:2001057 reactive nitrogen species metabolic process
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
