The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q53YK7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0001933 negative regulation of protein phosphorylation GO:0006979 response to oxidative stress GO:0007611 learning or memory GO:0010942 positive regulation of cell death GO:0032147 activation of protein kinase activity GO:0032689 negative regulation of interferon-gamma production GO:0032700 negative regulation of interleukin-17 production GO:0032703 negative regulation of interleukin-2 production GO:0032880 regulation of protein localization GO:0035584 calcium-mediated signaling using intracellular calcium source GO:0035690 cellular response to drug GO:0043066 negative regulation of apoptotic process GO:0043086 negative regulation of catalytic activity GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity GO:0046007 negative regulation of activated T cell proliferation GO:0046686 response to cadmium ion GO:0046688 response to copper ion GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation GO:0050860 negative regulation of T cell receptor signaling pathway GO:0051260 protein homooligomerization GO:0070885 negative regulation of calcineurin-NFAT signaling cascade GO:0090314 positive regulation of protein targeting to membrane GO:0090647 modulation of age-related behavioral decline GO:1900272 negative regulation of long-term synaptic potentiation GO:1900449 regulation of glutamate receptor signaling pathway GO:1901216 positive regulation of neuron death GO:1901379 regulation of potassium ion transmembrane transport GO:1902430 negative regulation of beta-amyloid formation GO:1902951 negative regulation of dendritic spine maintenance GO:1902992 negative regulation of amyloid precursor protein catabolic process GO:1903078 positive regulation of protein localization to plasma membrane GO:1904645 response to beta-amyloid GO:1904646 cellular response to beta-amyloid GO:1905664 regulation of calcium ion import across plasma membrane GO:1990535 neuron projection maintenance
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
