Human Gene PSMD8 (ENST00000215071.9_7) from GENCODE V47lift37
  Description: proteasome 26S subunit, non-ATPase 8 (from RefSeq NM_002812.5)
Gencode Transcript: ENST00000215071.9_7
Gencode Gene: ENSG00000099341.13_17
Transcript (Including UTRs)
   Position: hg19 chr19:38,865,211-38,874,464 Size: 9,254 Total Exon Count: 7 Strand: +
Coding Region
   Position: hg19 chr19:38,865,242-38,874,030 Size: 8,789 Coding Exon Count: 7 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:38,865,211-38,874,464)mRNA (may differ from genome)Protein (350 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 87.40 RPKM in Muscle - Skeletal
Total median expression: 1954.86 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -6.8031-0.219 Picture PostScript Text
3' UTR -155.70434-0.359 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologGenome Browser
Gene DetailsGene Details   Gene Details
Gene SorterGene Sorter   Gene Sorter
 RGDEnsembl  SGD
     Protein Sequence
     Alignment

-  Descriptions from all associated GenBank mRNAs
  AK301771 - Homo sapiens cDNA FLJ56327 complete cds, highly similar to 26S proteasome non-ATPase regulatory subunit 8.
EU668354 - Homo sapiens epididymis secretory sperm binding protein Li 91n (HEL-S-91n) mRNA, complete cds.
AK304486 - Homo sapiens cDNA FLJ52462 complete cds, moderately similar to Mus musculus proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (Psmd8), mRNA.
BC001164 - Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8, mRNA (cDNA clone MGC:1660 IMAGE:3528096), complete cds.
JD529842 - Sequence 510866 from Patent EP1572962.
D38047 - Homo sapiens mRNA for 26S proteasome subunit p31, complete cds.
BC065006 - Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8, mRNA (cDNA clone MGC:70340 IMAGE:6055235), complete cds.
JD464611 - Sequence 445635 from Patent EP1572962.
AB464081 - Synthetic construct DNA, clone: pF1KB8247, Homo sapiens PSMD8 gene for proteasome (prosome, macropain) 26S subunit, non-ATPase, 8, without stop codon, in Flexi system.
CU674590 - Synthetic construct Homo sapiens gateway clone IMAGE:100018062 5' read PSMD8 mRNA.
KJ901673 - Synthetic construct Homo sapiens clone ccsbBroadEn_11067 PSMD8 gene, encodes complete protein.
E11295 - Human cDNA encoding P31 which is involved in 26S proteasome.
BT019688 - Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 mRNA, complete cds.
AK308809 - Homo sapiens cDNA, FLJ98850.
JD358004 - Sequence 339028 from Patent EP1572962.
JD277001 - Sequence 258025 from Patent EP1572962.
JD501588 - Sequence 482612 from Patent EP1572962.
JD463587 - Sequence 444611 from Patent EP1572962.
JD162579 - Sequence 143603 from Patent EP1572962.
JD232536 - Sequence 213560 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000215071.1, ENST00000215071.2, ENST00000215071.3, ENST00000215071.4, ENST00000215071.5, ENST00000215071.6, ENST00000215071.7, ENST00000215071.8, HEL-S-91n , NM_002812, uc317clr.1, uc317clr.2, V9HW09, V9HW09_HUMAN
UCSC ID: ENST00000215071.9_7
RefSeq Accession: NM_002812.5

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.