ID:RABE2_HUMAN DESCRIPTION: RecName: Full=Rab GTPase-binding effector protein 2; AltName: Full=Rabaptin-5beta; FUNCTION: Plays a role in membrane trafficking and in homotypic early endosome fusion. SUBUNIT: Heterodimer with RABGEF1. The dimer binds RAB5A that has been activated by GTP-binding. SUBCELLULAR LOCATION: Cytoplasm. Early endosome. SIMILARITY: Belongs to the rabaptin family. SEQUENCE CAUTION: Sequence=BAB15594.1; Type=Frameshift; Positions=524;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9H5N1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006897 endocytosis GO:0010469 regulation of receptor activity GO:0015031 protein transport GO:0043547 positive regulation of GTPase activity