The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9HBD1
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0003677 DNA binding GO:0003723 RNA binding GO:0003725 double-stranded RNA binding GO:0003729 mRNA binding GO:0004842 ubiquitin-protein transferase activity GO:0016740 transferase activity GO:0035613 RNA stem-loop binding GO:0046872 metal ion binding
Biological Process: GO:0000209 protein polyubiquitination GO:0001782 B cell homeostasis GO:0006357 regulation of transcription from RNA polymerase II promoter GO:0009791 post-embryonic development GO:0010468 regulation of gene expression GO:0010608 posttranscriptional regulation of gene expression GO:0016567 protein ubiquitination GO:0035264 multicellular organism growth GO:0042098 T cell proliferation GO:0043029 T cell homeostasis GO:0048286 lung alveolus development GO:0048535 lymph node development GO:0048536 spleen development GO:0050852 T cell receptor signaling pathway GO:0060173 limb development GO:0061470 T follicular helper cell differentiation GO:1901224 positive regulation of NIK/NF-kappaB signaling GO:2000320 negative regulation of T-helper 17 cell differentiation GO:2000628 regulation of miRNA metabolic process