Human Gene RGS3 (ENST00000695401.1_4) from GENCODE V47lift37
  Description: regulator of G protein signaling 3, transcript variant 6 (from RefSeq NM_144488.8)
Gencode Transcript: ENST00000695401.1_4
Gencode Gene: ENSG00000138835.24_12
Transcript (Including UTRs)
   Position: hg19 chr9:116,226,007-116,360,018 Size: 134,012 Total Exon Count: 23 Strand: +
Coding Region
   Position: hg19 chr9:116,226,083-116,359,233 Size: 133,151 Coding Exon Count: 23 

Page IndexSequence and LinksPrimersCTDGene AllelesMicroarray Expression
RNA StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:116,226,007-116,360,018)mRNA (may differ from genome)Protein (1086 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -27.1076-0.357 Picture PostScript Text
3' UTR -337.00785-0.429 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  AK128127 - Homo sapiens cDNA FLJ46248 fis, clone TESTI4021197, highly similar to Regulator of G-protein signaling 3.
AF490839 - Homo sapiens RGS3 isoform C2PA-RGS3 (RGS3) mRNA, complete cds; alternatively spliced.
AK125059 - Homo sapiens cDNA FLJ43069 fis, clone BRTHA3009037, highly similar to Regulator of G-protein signaling 3.
AK074977 - Homo sapiens cDNA FLJ90496 fis, clone NT2RP3003849, weakly similar to PROTEIN KINASE C, BRAIN ISOZYME (EC 2.7.1.-).
AF463495 - Homo sapiens PDZ-RGS3 mRNA, complete cds.
AK096840 - Homo sapiens cDNA FLJ39521 fis, clone PUAEN2001586, highly similar to Regulator of G-protein signaling 3.
BC042555 - Homo sapiens regulator of G-protein signaling 3, mRNA (cDNA clone MGC:34286 IMAGE:5175121), complete cds.
CU692096 - Synthetic construct Homo sapiens gateway clone IMAGE:100023197 5' read RGS3 mRNA.
KJ897468 - Synthetic construct Homo sapiens clone ccsbBroadEn_06862 RGS3 gene, encodes complete protein.
AF490840 - Homo sapiens RGS3 isoform PDZ-RGS3 (RGS3) mRNA, complete cds; alternatively spliced.
AK000377 - Homo sapiens cDNA FLJ20370 fis, clone HEP19443.
AK222888 - Homo sapiens mRNA for Hypothetical protein FLJ90496 variant, clone: HEP19443.
LF206486 - JP 2014500723-A/13989: Polycomb-Associated Non-Coding RNAs.
AK123387 - Homo sapiens cDNA FLJ41393 fis, clone BRCAN2025982, highly similar to REGULATOR OF G-PROTEIN SIGNALING 3.
AK301515 - Homo sapiens cDNA FLJ60358 complete cds, highly similar to Regulator of G-protein signaling 3.
AK310705 - Homo sapiens cDNA, FLJ17747.
AK289666 - Homo sapiens cDNA FLJ77839 complete cds.
U27655 - Human RGP3 mRNA, complete cds.
AK125094 - Homo sapiens cDNA FLJ43104 fis, clone CTONG2010803, highly similar to Regulator of G-protein signaling 3.
AK226153 - Homo sapiens mRNA for regulator of G-protein signalling 3 isoform 6 variant, clone: sj01179.
AF493927 - Homo sapiens regulator of G protein signalling 3 (RGS3) mRNA, complete cds.
AY585192 - Homo sapiens regulator of G-protein signaling 3 mRNA, complete cds.
AF493941 - Homo sapiens regulator of G protein signalling 3 truncated (RGS3) mRNA, complete cds, alternatively spliced.
AK309971 - Homo sapiens cDNA, FLJ17013.
AF490838 - Homo sapiens RGS3 isoform RGS3S (RGS3) mRNA, complete cds; alternatively spliced.
AK054584 - Homo sapiens cDNA FLJ30022 fis, clone 3NB692001002, highly similar to REGULATOR OF G-PROTEIN SIGNALING 3.
BC018072 - Homo sapiens regulator of G-protein signaling 3, mRNA (cDNA clone IMAGE:4819528), partial cds.
BC019039 - Homo sapiens regulator of G-protein signaling 3, mRNA (cDNA clone IMAGE:4589325), partial cds.
CU676160 - Synthetic construct Homo sapiens gateway clone IMAGE:100018010 5' read RGS3 mRNA.
KJ901706 - Synthetic construct Homo sapiens clone ccsbBroadEn_11100 RGS3 gene, encodes complete protein.
LF211686 - JP 2014500723-A/19189: Polycomb-Associated Non-Coding RNAs.
JD219599 - Sequence 200623 from Patent EP1572962.
JD157132 - Sequence 138156 from Patent EP1572962.
JD361228 - Sequence 342252 from Patent EP1572962.
JD158115 - Sequence 139139 from Patent EP1572962.
JA215689 - Sequence 26 from Patent EP2310507.
LF382450 - JP 2014500723-A/189953: Polycomb-Associated Non-Coding RNAs.
JD332571 - Sequence 313595 from Patent EP1572962.
JD311532 - Sequence 292556 from Patent EP1572962.
JD469952 - Sequence 450976 from Patent EP1572962.
JD547272 - Sequence 528296 from Patent EP1572962.
JD355428 - Sequence 336452 from Patent EP1572962.
JD473764 - Sequence 454788 from Patent EP1572962.
LF382449 - JP 2014500723-A/189952: Polycomb-Associated Non-Coding RNAs.
JD318678 - Sequence 299702 from Patent EP1572962.
MA442063 - JP 2018138019-A/13989: Polycomb-Associated Non-Coding RNAs.
MA447263 - JP 2018138019-A/19189: Polycomb-Associated Non-Coding RNAs.
MA618027 - JP 2018138019-A/189953: Polycomb-Associated Non-Coding RNAs.
MA618026 - JP 2018138019-A/189952: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A8Q3WKG2, A0A8Q3WKG2_HUMAN, hCG_29191 , NM_144488, RGS3 , uc330zmp.1, uc330zmp.2
UCSC ID: ENST00000695401.1_4
RefSeq Accession: NM_001394167.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.