ID:RHOF_HUMAN DESCRIPTION: RecName: Full=Rho-related GTP-binding protein RhoF; AltName: Full=Rho family GTPase Rif; AltName: Full=Rho in filopodia; Flags: Precursor; FUNCTION: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin- based morphology. SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential). Cytoplasm, cytoskeleton. SIMILARITY: Belongs to the small GTPase superfamily. Rho family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9HBH0
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0007015 actin filament organization GO:0007264 small GTPase mediated signal transduction GO:0043312 neutrophil degranulation GO:0051056 regulation of small GTPase mediated signal transduction
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
