The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P40429
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AK301136 - Homo sapiens cDNA FLJ61175 complete cds, highly similar to SL cytokine precursor. AK130605 - Homo sapiens cDNA FLJ27095 fis, clone SPL04438, highly similar to 60S ribosomal protein L13A. D28409 - Homo sapiens mRNA for highly basic protein 23 kDa, 5'UTR region. BC105605 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone MGC:111166 IMAGE:6726477), complete cds. BC070223 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone MGC:88204 IMAGE:6736442), complete cds. AK056837 - Homo sapiens cDNA FLJ32275 fis, clone PROST2000053, moderately similar to 60S RIBOSOMAL PROTEIN L13A. AK291120 - Homo sapiens cDNA FLJ75551 complete cds, highly similar to Homo sapiens ribosomal protein L13a (RPL13A), mRNA. AK297859 - Homo sapiens cDNA FLJ51256 complete cds, highly similar to 60S ribosomal protein L13a. X56932 - H.sapiens mRNA for 23 kD highly basic protein. BC032107 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone IMAGE:4644246). BC065236 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone MGC:70840 IMAGE:6161599), complete cds. AF109186 - Homo sapiens FWP004 mRNA, complete cds. BC071921 - Homo sapiens cDNA clone IMAGE:6423605, **** WARNING: chimeric clone ****. BC071929 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone MGC:88614 IMAGE:5808487), complete cds. BC000514 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone MGC:8547 IMAGE:2822802), complete cds. BC001675 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone MGC:2546 IMAGE:2961667), complete cds. BC001836 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone MGC:4241 IMAGE:2961667), complete cds. AK222747 - Homo sapiens mRNA for ribosomal protein L13a variant, clone: DMC05308. BC062537 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone MGC:71249 IMAGE:4908022), complete cds. CU687556 - Synthetic construct Homo sapiens gateway clone IMAGE:100022338 5' read RPL13A mRNA. AB529025 - Synthetic construct DNA, clone: pF1KB3388, Homo sapiens RPL13A gene for ribosomal protein L13a, without stop codon, in Flexi system. KJ906094 - Synthetic construct Homo sapiens clone ccsbBroadEn_15764 RPL13A gene, encodes complete protein. EU831542 - Synthetic construct Homo sapiens clone HAIB:100066571; DKFZo004E0718 ribosomal protein L13a protein (RPL13A) gene, encodes complete protein. HQ447707 - Synthetic construct Homo sapiens clone IMAGE:100071035; CCSB013763_03 ribosomal protein L13a (RPL13A) gene, encodes complete protein. KJ893391 - Synthetic construct Homo sapiens clone ccsbBroadEn_02785 RPL13A gene, encodes complete protein. KJ898501 - Synthetic construct Homo sapiens clone ccsbBroadEn_07895 RPL13A gene, encodes complete protein. EU831455 - Synthetic construct Homo sapiens clone HAIB:100066484; DKFZo008E0717 ribosomal protein L13a protein (RPL13A) gene, encodes complete protein. GQ891317 - Homo sapiens clone HEL-S-40a epididymis secretory sperm binding protein mRNA, complete cds. BC013230 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone IMAGE:3462928). BC004900 - Homo sapiens ribosomal protein L13a, mRNA (cDNA clone IMAGE:3545758), partial cds. JD404540 - Sequence 385564 from Patent EP1572962. AB082924 - Homo sapiens RPL13a mRNA for ribosomal protein L13a, complete cds. JD055804 - Sequence 36828 from Patent EP1572962. JD022836 - Sequence 3860 from Patent EP1572962. U58669 - Human mRNA upregulated during camptothecin-induced apoptosis of U937 cells. JD440407 - Sequence 421431 from Patent EP1572962. JD439403 - Sequence 420427 from Patent EP1572962. JD386490 - Sequence 367514 from Patent EP1572962. JD114343 - Sequence 95367 from Patent EP1572962. JD354504 - Sequence 335528 from Patent EP1572962. JD193902 - Sequence 174926 from Patent EP1572962. JD193903 - Sequence 174927 from Patent EP1572962. JD221952 - Sequence 202976 from Patent EP1572962. BC000847 - Homo sapiens cDNA clone IMAGE:3458102. JD434834 - Sequence 415858 from Patent EP1572962. JD374311 - Sequence 355335 from Patent EP1572962. JD088484 - Sequence 69508 from Patent EP1572962. JD092633 - Sequence 73657 from Patent EP1572962. JD431984 - Sequence 413008 from Patent EP1572962. JD289622 - Sequence 270646 from Patent EP1572962. JD449309 - Sequence 430333 from Patent EP1572962. JD285448 - Sequence 266472 from Patent EP1572962. JD119519 - Sequence 100543 from Patent EP1572962. JD378378 - Sequence 359402 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein P40429 (Reactome details) participates in the following event(s):
R-HSA-156832 INF-gamma induced phosphorylation of L13a R-HSA-156826 Dissociation of L13a from the 60s ribosomal subunit R-HSA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA R-HSA-72672 The 60S subunit joins the translation initiation complex R-HSA-72673 Release of 40S and 60S subunits from the 80S ribosome R-HSA-72671 eIF5B:GTP is hydrolyzed and released R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA R-HSA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex R-HSA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) R-HSA-156923 Hydrolysis of eEF1A:GTP R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum R-HSA-156827 L13a-mediated translation R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-72613 Eukaryotic Translation Initiation R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-72737 Cap-dependent Translation Initiation R-HSA-8868773 rRNA processing in the nucleus and cytosol R-HSA-72766 Translation R-HSA-156902 Peptide chain elongation R-HSA-2408557 Selenocysteine synthesis R-HSA-72764 Eukaryotic Translation Termination R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-376176 Signaling by ROBO receptors R-HSA-192823 Viral mRNA Translation R-HSA-72312 rRNA processing R-HSA-392499 Metabolism of proteins R-HSA-156842 Eukaryotic Translation Elongation R-HSA-2408522 Selenoamino acid metabolism R-HSA-927802 Nonsense-Mediated Decay (NMD) R-HSA-422475 Axon guidance R-HSA-168273 Influenza Viral RNA Transcription and Replication R-HSA-8953854 Metabolism of RNA R-HSA-71291 Metabolism of nitrogenous molecules R-HSA-1266738 Developmental Biology R-HSA-168255 Influenza Life Cycle R-HSA-1430728 Metabolism R-HSA-168254 Influenza Infection R-HSA-5663205 Infectious disease R-HSA-1643685 Disease