ID:RL19_HUMAN DESCRIPTION: RecName: Full=60S ribosomal protein L19; SIMILARITY: Belongs to the ribosomal protein L19e family. SEQUENCE CAUTION: Sequence=CAD97677.1; Type=Erroneous initiation;
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
SCOP Domains: 48140 - Ribosomal protein L19 (L19e)
ModBase Predicted Comparative 3D Structure on P84098
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
BC095445 - Homo sapiens ribosomal protein L19, mRNA (cDNA clone MGC:111176 IMAGE:30721753), complete cds. AB055766 - Homo sapiens mRNA for ribosomal protein L19, partial cds. BC066315 - Homo sapiens ribosomal protein L19, mRNA (cDNA clone MGC:87178 IMAGE:5287470), complete cds. AK311858 - Homo sapiens cDNA, FLJ92124, Homo sapiens ribosomal protein L19 (RPL19), mRNA. AK130962 - Homo sapiens cDNA FLJ27452 fis, clone DMC06008. X63527 - H.sapiens mRNA for ribosomal protein L19. BC062709 - Homo sapiens ribosomal protein L19, mRNA (cDNA clone MGC:71997 IMAGE:6457109), complete cds. AK223082 - Homo sapiens mRNA for ribosomal protein L19 variant, clone: KAT01533. BX537435 - Homo sapiens mRNA; cDNA DKFZp779D216 (from clone DKFZp779D216). BC000530 - Homo sapiens ribosomal protein L19, mRNA (cDNA clone MGC:8653 IMAGE:2961653), complete cds. S56985 - ribosomal protein L19 [human, breast cancer cell line, MCF-7, mRNA, 690 nt]. BC013016 - Homo sapiens ribosomal protein L19, mRNA (cDNA clone MGC:4526 IMAGE:3010178), complete cds. CU674258 - Synthetic construct Homo sapiens gateway clone IMAGE:100018012 5' read RPL19 mRNA. EU831953 - Synthetic construct Homo sapiens clone HAIB:100066982; DKFZo008E0623 ribosomal protein L19 protein (RPL19) gene, encodes complete protein. EU832047 - Synthetic construct Homo sapiens clone HAIB:100067076; DKFZo004E0624 ribosomal protein L19 protein (RPL19) gene, encodes complete protein. DQ891377 - Synthetic construct clone IMAGE:100004007; FLH176348.01X; RZPDo839C04122D ribosomal protein L19 (RPL19) gene, encodes complete protein. HQ447194 - Synthetic construct Homo sapiens clone IMAGE:100070488; CCSB004703_02 ribosomal protein L19 (RPL19) gene, encodes complete protein. KJ892029 - Synthetic construct Homo sapiens clone ccsbBroadEn_01423 RPL19 gene, encodes complete protein. AY157980 - Homo sapiens ribosomal protein L19 mRNA, partial cds. DQ580256 - Homo sapiens piRNA piR-48368, complete sequence. JD269283 - Sequence 250307 from Patent EP1572962. AB019566 - Homo sapiens mRNA expressed only in placental villi, clone SMAP67. JD361796 - Sequence 342820 from Patent EP1572962. JD296163 - Sequence 277187 from Patent EP1572962. JD160288 - Sequence 141312 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein P84098 (Reactome details) participates in the following event(s):
R-HSA-72672 The 60S subunit joins the translation initiation complex R-HSA-156826 Dissociation of L13a from the 60s ribosomal subunit R-HSA-72673 Release of 40S and 60S subunits from the 80S ribosome R-HSA-72671 eIF5B:GTP is hydrolyzed and released R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA R-HSA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex R-HSA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) R-HSA-156923 Hydrolysis of eEF1A:GTP R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-156827 L13a-mediated translation R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-72737 Cap-dependent Translation Initiation R-HSA-72613 Eukaryotic Translation Initiation R-HSA-8868773 rRNA processing in the nucleus and cytosol R-HSA-156902 Peptide chain elongation R-HSA-2408557 Selenocysteine synthesis R-HSA-72764 Eukaryotic Translation Termination R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-72766 Translation R-HSA-376176 Signaling by ROBO receptors R-HSA-192823 Viral mRNA Translation R-HSA-72312 rRNA processing R-HSA-156842 Eukaryotic Translation Elongation R-HSA-2408522 Selenoamino acid metabolism R-HSA-927802 Nonsense-Mediated Decay (NMD) R-HSA-392499 Metabolism of proteins R-HSA-422475 Axon guidance R-HSA-168273 Influenza Viral RNA Transcription and Replication R-HSA-8953854 Metabolism of RNA R-HSA-71291 Metabolism of nitrogenous molecules R-HSA-1266738 Developmental Biology R-HSA-168255 Influenza Life Cycle R-HSA-1430728 Metabolism R-HSA-168254 Influenza Infection R-HSA-5663205 Infectious disease R-HSA-1643685 Disease
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
