The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF01776 - Ribosomal L22e protein family
ModBase Predicted Comparative 3D Structure on Q6P5R6
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
LF383788 - JP 2014500723-A/191291: Polycomb-Associated Non-Coding RNAs. JD057512 - Sequence 38536 from Patent EP1572962. JD056292 - Sequence 37316 from Patent EP1572962. JD186669 - Sequence 167693 from Patent EP1572962. JD270726 - Sequence 251750 from Patent EP1572962. JD228247 - Sequence 209271 from Patent EP1572962. JD503562 - Sequence 484586 from Patent EP1572962. JD552780 - Sequence 533804 from Patent EP1572962. JD509565 - Sequence 490589 from Patent EP1572962. JD268252 - Sequence 249276 from Patent EP1572962. JD081027 - Sequence 62051 from Patent EP1572962. JD420382 - Sequence 401406 from Patent EP1572962. JD254642 - Sequence 235666 from Patent EP1572962. JD254752 - Sequence 235776 from Patent EP1572962. JD321478 - Sequence 302502 from Patent EP1572962. JD264520 - Sequence 245544 from Patent EP1572962. JD264725 - Sequence 245749 from Patent EP1572962. JD342490 - Sequence 323514 from Patent EP1572962. JD342489 - Sequence 323513 from Patent EP1572962. JD239653 - Sequence 220677 from Patent EP1572962. JD365192 - Sequence 346216 from Patent EP1572962. JD270144 - Sequence 251168 from Patent EP1572962. JD405467 - Sequence 386491 from Patent EP1572962. JD209742 - Sequence 190766 from Patent EP1572962. JD507578 - Sequence 488602 from Patent EP1572962. JD552376 - Sequence 533400 from Patent EP1572962. JD555331 - Sequence 536355 from Patent EP1572962. JD072931 - Sequence 53955 from Patent EP1572962. JD453948 - Sequence 434972 from Patent EP1572962. JD437859 - Sequence 418883 from Patent EP1572962. JD563371 - Sequence 544395 from Patent EP1572962. BC107708 - Homo sapiens ribosomal protein L22-like 1, mRNA (cDNA clone MGC:104449 IMAGE:6618915), complete cds. LF206090 - JP 2014500723-A/13593: Polycomb-Associated Non-Coding RNAs. AL110170 - Homo sapiens mRNA; cDNA DKFZp586O1224 (from clone DKFZp586O1224). BC062731 - Homo sapiens ribosomal protein L22-like 1, mRNA (cDNA clone IMAGE:6735782), partial cds. BC049823 - Homo sapiens ribosomal protein L22-like 1, mRNA (cDNA clone IMAGE:4865966), **** WARNING: chimeric clone ****. LF210220 - JP 2014500723-A/17723: Polycomb-Associated Non-Coding RNAs. KJ900416 - Synthetic construct Homo sapiens clone ccsbBroadEn_09810 RPL22L1 gene, encodes complete protein. LF351258 - JP 2014500723-A/158761: Polycomb-Associated Non-Coding RNAs. MA619365 - JP 2018138019-A/191291: Polycomb-Associated Non-Coding RNAs. MA586835 - JP 2018138019-A/158761: Polycomb-Associated Non-Coding RNAs. MA441667 - JP 2018138019-A/13593: Polycomb-Associated Non-Coding RNAs. MA445797 - JP 2018138019-A/17723: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q6P5R6 (Reactome details) participates in the following event(s):
R-HSA-72672 The 60S subunit joins the translation initiation complex R-HSA-156826 Dissociation of L13a from the 60s ribosomal subunit R-HSA-72673 Release of 40S and 60S subunits from the 80S ribosome R-HSA-72671 eIF5B:GTP is hydrolyzed and released R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA R-HSA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex R-HSA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) R-HSA-156923 Hydrolysis of eEF1A:GTP R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-156827 L13a-mediated translation R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-72737 Cap-dependent Translation Initiation R-HSA-72613 Eukaryotic Translation Initiation R-HSA-8868773 rRNA processing in the nucleus and cytosol R-HSA-156902 Peptide chain elongation R-HSA-2408557 Selenocysteine synthesis R-HSA-72764 Eukaryotic Translation Termination R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-72766 Translation R-HSA-376176 Signaling by ROBO receptors R-HSA-192823 Viral mRNA Translation R-HSA-72312 rRNA processing R-HSA-156842 Eukaryotic Translation Elongation R-HSA-2408522 Selenoamino acid metabolism R-HSA-927802 Nonsense-Mediated Decay (NMD) R-HSA-392499 Metabolism of proteins R-HSA-422475 Axon guidance R-HSA-168273 Influenza Viral RNA Transcription and Replication R-HSA-8953854 Metabolism of RNA R-HSA-71291 Metabolism of nitrogenous molecules R-HSA-1266738 Developmental Biology R-HSA-168255 Influenza Life Cycle R-HSA-1430728 Metabolism R-HSA-168254 Influenza Infection R-HSA-5663205 Infectious disease R-HSA-1643685 Disease
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
