Human Gene RPL32 (ENST00000273223.10_5) from GENCODE V47lift37
  Description: Belongs to the eukaryotic ribosomal protein eL32 family. (from UniProt F8W727)
Gencode Transcript: ENST00000273223.10_5
Gencode Gene: ENSG00000144713.13_9
Transcript (Including UTRs)
   Position: hg19 chr3:12,877,546-12,883,045 Size: 5,500 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chr3:12,877,593-12,881,736 Size: 4,144 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsPrimersMalaCardsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:12,877,546-12,883,045)mRNA (may differ from genome)Protein (153 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsHGNC
MalacardsMGIPubMedUniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: F8W727_HUMAN
DESCRIPTION: SubName: Full=60S ribosomal protein L32;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: RPL32
Diseases sorted by gene-association score: malignant melanoma, somatic (1)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 681.02 RPKM in Ovary
Total median expression: 14451.68 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -16.3058-0.281 Picture PostScript Text
3' UTR -4.8047-0.102 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001515 - Ribosomal_L32e

Pfam Domains:
PF01655 - Ribosomal protein L32

SCOP Domains:
52042 - Ribosomal protein L32e

ModBase Predicted Comparative 3D Structure on F8W727
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003735 structural constituent of ribosome

Biological Process:
GO:0006412 translation

Cellular Component:
GO:0005622 intracellular
GO:0005840 ribosome


-  Descriptions from all associated GenBank mRNAs
  X03342 - Human mRNA for ribosomal protein L32.
K03002 - Human mRNA from chromosome 15 gene with homology to MHC-HLA-SB-1 intron A.
BC011514 - Homo sapiens ribosomal protein L32, mRNA (cDNA clone MGC:5212 IMAGE:2900089), complete cds.
AK124029 - Homo sapiens cDNA FLJ42035 fis, clone SPLEN2038180.
BC070209 - Homo sapiens ribosomal protein L32, mRNA (cDNA clone MGC:88190 IMAGE:6738371), complete cds.
JD423105 - Sequence 404129 from Patent EP1572962.
JD479834 - Sequence 460858 from Patent EP1572962.
DQ891573 - Synthetic construct clone IMAGE:100004203; FLH178276.01X; RZPDo839B04128D ribosomal protein L32 (RPL32) gene, encodes complete protein.
AK311909 - Homo sapiens cDNA, FLJ92175, Homo sapiens ribosomal protein L32 (RPL32), mRNA.
KJ892040 - Synthetic construct Homo sapiens clone ccsbBroadEn_01434 RPL32 gene, encodes complete protein.
DQ894767 - Synthetic construct Homo sapiens clone IMAGE:100009227; FLH178272.01L; RZPDo839B04127D ribosomal protein L32 (RPL32) gene, encodes complete protein.
DQ574254 - Homo sapiens piRNA piR-42366, complete sequence.
DL492320 - Novel nucleic acids.
DL490812 - Novel nucleic acids.
DQ570485 - Homo sapiens piRNA piR-30597, complete sequence.
LF332515 - JP 2014500723-A/140018: Polycomb-Associated Non-Coding RNAs.
D28385 - Homo sapiens mRNA for ribosomal protein L32, partial cds.
MA568092 - JP 2018138019-A/140018: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000273223.1, ENST00000273223.2, ENST00000273223.3, ENST00000273223.4, ENST00000273223.5, ENST00000273223.6, ENST00000273223.7, ENST00000273223.8, ENST00000273223.9, F8W727, F8W727_HUMAN, RPL32 , uc317jbh.1, uc317jbh.2, X03342
UCSC ID: ENST00000273223.10_5
RefSeq Accession: NM_001007073.1
Protein: F8W727

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.