The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on P15880
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
BC016178 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:17896 IMAGE:3909865), complete cds. BC106060 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:117345 IMAGE:6471612), complete cds. BC008329 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone IMAGE:3504130). BC021545 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:15956 IMAGE:3538227), complete cds. AB065088 - Homo sapiens OK/KNS-cl.6 mRNA for ribosomal protein S2, complete cds. BC012354 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:20390 IMAGE:4564801), complete cds. BC004520 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone IMAGE:3938975), partial cds. AB082925 - Homo sapiens rps2 mRNA for ribosomal protein S2, complete cds. BC019021 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone IMAGE:4547162). BC001795 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:3141 IMAGE:3353508), complete cds. BC006559 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:2778 IMAGE:2959602), complete cds. BC008862 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:16692 IMAGE:4126765), complete cds. BC010165 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:19832 IMAGE:4040679), complete cds. BC011661 - Homo sapiens cDNA clone IMAGE:4130973, **** WARNING: chimeric clone ****. BC013833 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone IMAGE:4149435). BC016951 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:21506 IMAGE:3883854), complete cds. BC018993 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:20302 IMAGE:4127411), complete cds. BC023541 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:15421 IMAGE:4120795), complete cds. BC025677 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:35569 IMAGE:5203563), complete cds. BC029979 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone IMAGE:4389294). BC032129 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:29707 IMAGE:5019977), complete cds. BC035427 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone IMAGE:3446871). BC052235 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone IMAGE:5441798), partial cds. BC063011 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone IMAGE:5217154), partial cds. BC063508 - Homo sapiens cDNA clone IMAGE:3861495, **** WARNING: chimeric clone ****. BC071673 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:87874 IMAGE:4540360), complete cds. BC071922 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:88607 IMAGE:5455280), complete cds. BC071923 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:88608 IMAGE:5477295), complete cds. BC071924 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:88609 IMAGE:6729920), complete cds. BC073966 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:87875 IMAGE:6047887), complete cds. BC075830 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:88606 IMAGE:5441508), complete cds. AB065089 - Homo sapiens OK/KNS-cl.7 mRNA for ribosomal protein S2, complete cds. BC068051 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:78476 IMAGE:4853351), complete cds. BC103756 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:117344 IMAGE:6008803), complete cds. BC105985 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:102851 IMAGE:5114688), complete cds. BC066321 - Homo sapiens ribosomal protein S2, mRNA (cDNA clone MGC:87212 IMAGE:5296344), complete cds. X17206 - Human mRNA for LLRep3. DQ892445 - Synthetic construct clone IMAGE:100005075; FLH186385.01X; RZPDo839D1271D ribosomal protein S2 (RPS2) gene, encodes complete protein. AK312173 - Homo sapiens cDNA, FLJ92460, Homo sapiens ribosomal protein S2 (RPS2), mRNA. CU689286 - Synthetic construct Homo sapiens gateway clone IMAGE:100021918 5' read RPS2 mRNA. KJ897496 - Synthetic construct Homo sapiens clone ccsbBroadEn_06890 RPS2 gene, encodes complete protein. KJ897497 - Synthetic construct Homo sapiens clone ccsbBroadEn_06891 RPS2 gene, encodes complete protein. DQ895656 - Synthetic construct Homo sapiens clone IMAGE:100010116; FLH186381.01L; RZPDo839D1261D ribosomal protein S2 (RPS2) gene, encodes complete protein. KJ905906 - Synthetic construct Homo sapiens clone ccsbBroadEn_15576 RPS2 gene, encodes complete protein. KJ905907 - Synthetic construct Homo sapiens clone ccsbBroadEn_15577 RPS2 gene, encodes complete protein. AB529037 - Synthetic construct DNA, clone: pF1KB3450, Homo sapiens RPS2 gene for ribosomal protein S2, without stop codon, in Flexi system. CU677775 - Synthetic construct Homo sapiens gateway clone IMAGE:100016983 5' read RPS2 mRNA. CU680300 - Synthetic construct Homo sapiens gateway clone IMAGE:100016984 5' read RPS2 mRNA. JD026120 - Sequence 7144 from Patent EP1572962. DL492626 - Novel nucleic acids. DL492625 - Novel nucleic acids. CU677585 - Synthetic construct Homo sapiens gateway clone IMAGE:100020674 5' read RPS2 mRNA. JD025077 - Sequence 6101 from Patent EP1572962. JD026395 - Sequence 7419 from Patent EP1572962. JD019945 - Sequence 969 from Patent EP1572962. JD036149 - Sequence 17173 from Patent EP1572962. JD032746 - Sequence 13770 from Patent EP1572962. JD035171 - Sequence 16195 from Patent EP1572962. JD023071 - Sequence 4095 from Patent EP1572962. JD127964 - Sequence 108988 from Patent EP1572962. JD019964 - Sequence 988 from Patent EP1572962. JD030352 - Sequence 11376 from Patent EP1572962. JD279058 - Sequence 260082 from Patent EP1572962. AB055772 - Homo sapiens mRNA for ribosomal protein S2, partial cds.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein P15880 (Reactome details) participates in the following event(s):
R-HSA-8879123 PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 R-HSA-72676 eIF3 and eIF1A bind to the 40S subunit R-HSA-72673 Release of 40S and 60S subunits from the 80S ribosome R-HSA-72672 The 60S subunit joins the translation initiation complex R-HSA-72619 eIF2:GTP is hydrolyzed, eIFs are released R-HSA-72691 Formation of the 43S pre-initiation complex R-HSA-156808 Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation R-HSA-157849 Formation of translation initiation complexes containing mRNA that does not circularize R-HSA-6790906 EMG1 of the SSU processome methylates pseudouridine-1248 of 18S rRNA yielding N(1)-methylpseudouridine-1248 R-HSA-72671 eIF5B:GTP is hydrolyzed and released R-HSA-156907 Aminoacyl-tRNA binds to the ribosome at the A-site R-HSA-2408529 Sec-tRNA(Sec):EEFSEC:GTP binds to 80S Ribosome R-HSA-141691 GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex R-HSA-156915 Translocation of ribosome by 3 bases in the 3' direction R-HSA-141671 Polypeptide release from the eRF3-GDP:eRF1:mRNA:80S Ribosome complex R-HSA-156912 Peptide transfer from P-site tRNA to the A-site tRNA R-HSA-927832 UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex R-HSA-927789 Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex R-HSA-1799332 Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) R-HSA-156923 Hydrolysis of eEF1A:GTP R-HSA-72621 Ribosomal scanning R-HSA-72697 Start codon recognition R-HSA-156823 Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA R-HSA-5333615 80S:Met-tRNAi:mRNA:SECISBP2:Sec-tRNA(Sec):EEFSEC:GTP is hydrolysed to 80S:Met-tRNAi:mRNA:SECISBP2:Sec and EEFSEC:GDP by EEFSEC R-HSA-141673 GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex R-HSA-927889 SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) R-HSA-1799329 Signal peptidase hydrolyzes signal peptide from ribosome-associated nascent protein R-HSA-1799330 The SRP receptor binds the SRP:nascent peptide:ribosome complex R-HSA-1799326 Signal-containing nascent peptide translocates to endoplasmic reticulum R-HSA-3214858 RMTs methylate histone arginines R-HSA-8876725 Protein methylation R-HSA-72689 Formation of a pool of free 40S subunits R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol R-HSA-3247509 Chromatin modifying enzymes R-HSA-597592 Post-translational protein modification R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane R-HSA-9010553 Regulation of expression of SLITs and ROBOs R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex R-HSA-72649 Translation initiation complex formation R-HSA-72737 Cap-dependent Translation Initiation R-HSA-8868773 rRNA processing in the nucleus and cytosol R-HSA-4839726 Chromatin organization R-HSA-392499 Metabolism of proteins R-HSA-6790901 rRNA modification in the nucleus and cytosol R-HSA-156902 Peptide chain elongation R-HSA-2408557 Selenocysteine synthesis R-HSA-72764 Eukaryotic Translation Termination R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) R-HSA-72766 Translation R-HSA-376176 Signaling by ROBO receptors R-HSA-192823 Viral mRNA Translation R-HSA-72702 Ribosomal scanning and start codon recognition R-HSA-156827 L13a-mediated translation R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S R-HSA-72613 Eukaryotic Translation Initiation R-HSA-72312 rRNA processing R-HSA-156842 Eukaryotic Translation Elongation R-HSA-2408522 Selenoamino acid metabolism R-HSA-927802 Nonsense-Mediated Decay (NMD) R-HSA-422475 Axon guidance R-HSA-168273 Influenza Viral RNA Transcription and Replication R-HSA-8953854 Metabolism of RNA R-HSA-71291 Metabolism of nitrogenous molecules R-HSA-1266738 Developmental Biology R-HSA-168255 Influenza Life Cycle R-HSA-1430728 Metabolism R-HSA-168254 Influenza Infection R-HSA-5663205 Infectious disease R-HSA-1643685 Disease
US Server
Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
