Human Gene RPS21 (ENST00000343986.9_8) from GENCODE V47lift37
  Description: ribosomal protein S21 (from RefSeq NM_001024.4)
Gencode Transcript: ENST00000343986.9_8
Gencode Gene: ENSG00000171858.18_11
Transcript (Including UTRs)
   Position: hg19 chr20:60,962,159-60,963,576 Size: 1,418 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr20:60,962,395-60,963,522 Size: 1,128 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr20:60,962,159-60,963,576)mRNA (may differ from genome)Protein (83 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
HGNCMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: Q6FGH5_HUMAN
DESCRIPTION: RecName: Full=40S ribosomal protein S21; Flags: Fragment;
SIMILARITY: Belongs to the ribosomal protein S21e family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 455.88 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 9455.05 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -13.0052-0.250 Picture PostScript Text
3' UTR -4.1054-0.076 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001931 - Ribosomal_S21e
IPR018279 - Ribosomal_S21e_CS

Pfam Domains:
PF01249 - Ribosomal protein S21e

ModBase Predicted Comparative 3D Structure on Q6FGH5
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologGenome BrowserGenome Browser
Gene Details  Gene DetailsGene DetailsGene Details
Gene Sorter  Gene SorterGene SorterGene Sorter
    WormBaseSGD
    Protein SequenceProtein Sequence
    AlignmentAlignment

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003735 structural constituent of ribosome

Biological Process:
GO:0006412 translation

Cellular Component:
GO:0005622 intracellular
GO:0005840 ribosome


-  Descriptions from all associated GenBank mRNAs
  BC021990 - Homo sapiens ribosomal protein S21, mRNA (cDNA clone MGC:24397 IMAGE:4066330), complete cds.
D28422 - Homo sapiens mRNA for ribosomal protein S21, partial cds.
L04483 - Human ribosomal protein S21 (RPS21) mRNA, complete cds.
BC027976 - Homo sapiens ribosomal protein S21, mRNA (cDNA clone IMAGE:5229149), with apparent retained intron.
X79563 - Homo sapiens mRNA for 8.2kDa differentiation factor.
BC071927 - Homo sapiens ribosomal protein S21, mRNA (cDNA clone IMAGE:4855963), with apparent retained intron.
BC018140 - Homo sapiens ribosomal protein S21, mRNA (cDNA clone MGC:9438 IMAGE:3903320), complete cds.
KJ901717 - Synthetic construct Homo sapiens clone ccsbBroadEn_11111 RPS21 gene, encodes complete protein.
DQ894759 - Synthetic construct Homo sapiens clone IMAGE:100009219; FLH178199.01L; RZPDo839A06127D ribosomal protein S21 (RPS21) gene, encodes complete protein.
DQ895017 - Synthetic construct Homo sapiens clone IMAGE:100009477; FLH263690.01L; RZPDo839B08133D ribosomal protein S21 (RPS21) gene, encodes complete protein.
DQ895029 - Synthetic construct Homo sapiens clone IMAGE:100009489; FLH263692.01L; RZPDo839C12133D ribosomal protein S21 (RPS21) gene, encodes complete protein.
DQ893580 - Synthetic construct Homo sapiens clone IMAGE:100006210; FLH263547.01X; RZPDo839D03128D ribosomal protein S21 (RPS21) gene, encodes complete protein.
DQ893582 - Synthetic construct clone IMAGE:100006212; FLH178203.01X; RZPDo839A06128D ribosomal protein S21 (RPS21) gene, encodes complete protein.
KJ897507 - Synthetic construct Homo sapiens clone ccsbBroadEn_06901 RPS21 gene, encodes complete protein.
CR542132 - Homo sapiens full open reading frame cDNA clone RZPDo834C1123D for gene RPS21, ribosomal protein S21; complete cds, without stopcodon.

-  Other Names for This Gene
  Alternate Gene Symbols: ENST00000343986.1, ENST00000343986.2, ENST00000343986.3, ENST00000343986.4, ENST00000343986.5, ENST00000343986.6, ENST00000343986.7, ENST00000343986.8, hCG_41768 , NM_001024, Q6FGH5, Q6FGH5_HUMAN, RPS21 , uc317wup.1, uc317wup.2
UCSC ID: ENST00000343986.9_8
RefSeq Accession: NM_001024.4
Protein: Q6FGH5

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.