The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q14684
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0001105 RNA polymerase II transcription coactivator activity GO:0003723 RNA binding GO:0005515 protein binding
Biological Process: GO:0006351 transcription, DNA-templated GO:0006355 regulation of transcription, DNA-templated GO:0006364 rRNA processing GO:0006366 transcription from RNA polymerase II promoter GO:0006397 mRNA processing GO:0006915 apoptotic process GO:0008380 RNA splicing GO:0010923 negative regulation of phosphatase activity GO:0034260 negative regulation of GTPase activity GO:0043065 positive regulation of apoptotic process GO:0043484 regulation of RNA splicing GO:0043923 positive regulation by host of viral transcription GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0098586 cellular response to virus