Human Gene SELENOP (ENST00000506577.5_4) from GENCODE V47lift37
Description: Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis. (from UniProt P49908) Gencode Transcript: ENST00000506577.5_4 Gencode Gene: ENSG00000250722.6_14 Transcript (Including UTRs) Position: hg19 chr5:42,800,233-42,825,998 Size: 25,766 Total Exon Count: 5 Strand: - Coding Region Position: hg19 chr5:42,800,822-42,808,455 Size: 7,634 Coding Exon Count: 4
ID:SEPP1_HUMAN DESCRIPTION: RecName: Full=Selenoprotein P; Short=SeP; Flags: Precursor; FUNCTION: Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis. SUBCELLULAR LOCATION: Secreted. TISSUE SPECIFICITY: Made in the liver and heart and secreted into the plasma. It is also found in the kidney. PTM: Phosphorylation sites are present in the extracellular medium. SIMILARITY: Belongs to the selenoprotein P family. WEB RESOURCE: Name=NIEHS-SNPs; URL="http://egp.gs.washington.edu/data/sepp1/";
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF04592 - Selenoprotein P, N terminal region PF04593 - Selenoprotein P, C terminal region
ModBase Predicted Comparative 3D Structure on P49908
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
