Human Gene SMG7 (ENST00000688051.1_3) from GENCODE V47lift37
  Description: SMG7 nonsense mediated mRNA decay factor, transcript variant 12 (from RefSeq NM_001375585.1)
Gencode Transcript: ENST00000688051.1_3
Gencode Gene: ENSG00000116698.22_18
Transcript (Including UTRs)
   Position: hg19 chr1:183,441,634-183,523,326 Size: 81,693 Total Exon Count: 23 Strand: +
Coding Region
   Position: hg19 chr1:183,441,756-183,521,066 Size: 79,311 Coding Exon Count: 23 

Page IndexSequence and LinksPrimersCTDGene AllelesMicroarray Expression
RNA StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:183,441,634-183,523,326)mRNA (may differ from genome)Protein (1187 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsHGNC
MGIOMIMPubMedUniProtKBWikipediaBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
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+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -61.00122-0.500 Picture PostScript Text
3' UTR -735.202260-0.325 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  AK297207 - Homo sapiens cDNA FLJ55570 partial cds, highly similar to Protein SMG7.
AK299178 - Homo sapiens cDNA FLJ61348 complete cds, highly similar to Protein SMG7.
LF205393 - JP 2014500723-A/12896: Polycomb-Associated Non-Coding RNAs.
AK091477 - Homo sapiens cDNA FLJ34158 fis, clone FCBBF3013589, weakly similar to GLUTENIN, LOW MOLECULAR WEIGHT SUBUNIT PRECURSOR.
AX747010 - Sequence 535 from Patent EP1308459.
AK056035 - Homo sapiens cDNA FLJ31473 fis, clone NT2NE2001530.
BC036381 - Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), mRNA (cDNA clone MGC:33347 IMAGE:4829267), complete cds.
AK307394 - Homo sapiens cDNA, FLJ97342.
AK074297 - Homo sapiens cDNA FLJ23717 fis, clone HEP13634.
D87437 - Homo sapiens mRNA for KIAA0250 gene.
AB085674 - Homo sapiens hsmg-7 mRNA for SMG-7, complete cds.
AB383819 - Synthetic construct DNA, clone: pF1KSDA0250, Homo sapiens SMG7 gene for Smg-7 homolog, nonsense mediated mRNA decay factor, complete cds, without stop codon, in Flexi system.
BC052565 - Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), mRNA (cDNA clone IMAGE:6337867), partial cds.
AY386363 - Homo sapiens breast cancer-associated antigen SGA-56M (SGA56M) mRNA, complete cds.
MA440970 - JP 2018138019-A/12896: Polycomb-Associated Non-Coding RNAs.
JD138733 - Sequence 119757 from Patent EP1572962.
LF320029 - JP 2014500723-A/127532: Polycomb-Associated Non-Coding RNAs.
LF319994 - JP 2014500723-A/127497: Polycomb-Associated Non-Coding RNAs.
MA555606 - JP 2018138019-A/127532: Polycomb-Associated Non-Coding RNAs.
MA555571 - JP 2018138019-A/127497: Polycomb-Associated Non-Coding RNAs.
LF319986 - JP 2014500723-A/127489: Polycomb-Associated Non-Coding RNAs.
LF319985 - JP 2014500723-A/127488: Polycomb-Associated Non-Coding RNAs.
AL833675 - Homo sapiens mRNA; cDNA DKFZp667P0221 (from clone DKFZp667P0221).
LF319984 - JP 2014500723-A/127487: Polycomb-Associated Non-Coding RNAs.
LF319983 - JP 2014500723-A/127486: Polycomb-Associated Non-Coding RNAs.
LF319981 - JP 2014500723-A/127484: Polycomb-Associated Non-Coding RNAs.
BC015788 - Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), mRNA (cDNA clone IMAGE:4864144), with apparent retained intron.
LF319973 - JP 2014500723-A/127476: Polycomb-Associated Non-Coding RNAs.
LF319972 - JP 2014500723-A/127475: Polycomb-Associated Non-Coding RNAs.
BC009281 - Homo sapiens Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans), mRNA (cDNA clone IMAGE:4135126).
JD114889 - Sequence 95913 from Patent EP1572962.
JD251335 - Sequence 232359 from Patent EP1572962.
JD564943 - Sequence 545967 from Patent EP1572962.
JD375220 - Sequence 356244 from Patent EP1572962.
JD134799 - Sequence 115823 from Patent EP1572962.
LF319971 - JP 2014500723-A/127474: Polycomb-Associated Non-Coding RNAs.
JD347910 - Sequence 328934 from Patent EP1572962.
JD056243 - Sequence 37267 from Patent EP1572962.
JD229862 - Sequence 210886 from Patent EP1572962.
LF319970 - JP 2014500723-A/127473: Polycomb-Associated Non-Coding RNAs.
JD263561 - Sequence 244585 from Patent EP1572962.
JD265772 - Sequence 246796 from Patent EP1572962.
JD474533 - Sequence 455557 from Patent EP1572962.
JD385564 - Sequence 366588 from Patent EP1572962.
JD468144 - Sequence 449168 from Patent EP1572962.
JD334924 - Sequence 315948 from Patent EP1572962.
JD136397 - Sequence 117421 from Patent EP1572962.
JD159153 - Sequence 140177 from Patent EP1572962.
LF319969 - JP 2014500723-A/127472: Polycomb-Associated Non-Coding RNAs.
JD239071 - Sequence 220095 from Patent EP1572962.
JD068882 - Sequence 49906 from Patent EP1572962.
JD080125 - Sequence 61149 from Patent EP1572962.
JD055581 - Sequence 36605 from Patent EP1572962.
JD268799 - Sequence 249823 from Patent EP1572962.
LF319968 - JP 2014500723-A/127471: Polycomb-Associated Non-Coding RNAs.
JD051634 - Sequence 32658 from Patent EP1572962.
JD456581 - Sequence 437605 from Patent EP1572962.
JD098101 - Sequence 79125 from Patent EP1572962.
JD216529 - Sequence 197553 from Patent EP1572962.
JD200051 - Sequence 181075 from Patent EP1572962.
JD415553 - Sequence 396577 from Patent EP1572962.
JD379040 - Sequence 360064 from Patent EP1572962.
LF319967 - JP 2014500723-A/127470: Polycomb-Associated Non-Coding RNAs.
LF319966 - JP 2014500723-A/127469: Polycomb-Associated Non-Coding RNAs.
JD490144 - Sequence 471168 from Patent EP1572962.
JD235410 - Sequence 216434 from Patent EP1572962.
JD548435 - Sequence 529459 from Patent EP1572962.
JD097210 - Sequence 78234 from Patent EP1572962.
JD467054 - Sequence 448078 from Patent EP1572962.
JD124077 - Sequence 105101 from Patent EP1572962.
JD375463 - Sequence 356487 from Patent EP1572962.
JD463968 - Sequence 444992 from Patent EP1572962.
JD142959 - Sequence 123983 from Patent EP1572962.
JD566286 - Sequence 547310 from Patent EP1572962.
JD290435 - Sequence 271459 from Patent EP1572962.
LF319965 - JP 2014500723-A/127468: Polycomb-Associated Non-Coding RNAs.
JD513784 - Sequence 494808 from Patent EP1572962.
JD393763 - Sequence 374787 from Patent EP1572962.
JD283711 - Sequence 264735 from Patent EP1572962.
JD546969 - Sequence 527993 from Patent EP1572962.
JD150657 - Sequence 131681 from Patent EP1572962.
LF319964 - JP 2014500723-A/127467: Polycomb-Associated Non-Coding RNAs.
JD111669 - Sequence 92693 from Patent EP1572962.
LF319963 - JP 2014500723-A/127466: Polycomb-Associated Non-Coding RNAs.
JD096075 - Sequence 77099 from Patent EP1572962.
MA555563 - JP 2018138019-A/127489: Polycomb-Associated Non-Coding RNAs.
MA555562 - JP 2018138019-A/127488: Polycomb-Associated Non-Coding RNAs.
MA555561 - JP 2018138019-A/127487: Polycomb-Associated Non-Coding RNAs.
MA555560 - JP 2018138019-A/127486: Polycomb-Associated Non-Coding RNAs.
MA555558 - JP 2018138019-A/127484: Polycomb-Associated Non-Coding RNAs.
MA555550 - JP 2018138019-A/127476: Polycomb-Associated Non-Coding RNAs.
MA555549 - JP 2018138019-A/127475: Polycomb-Associated Non-Coding RNAs.
MA555548 - JP 2018138019-A/127474: Polycomb-Associated Non-Coding RNAs.
MA555547 - JP 2018138019-A/127473: Polycomb-Associated Non-Coding RNAs.
MA555546 - JP 2018138019-A/127472: Polycomb-Associated Non-Coding RNAs.
MA555545 - JP 2018138019-A/127471: Polycomb-Associated Non-Coding RNAs.
MA555544 - JP 2018138019-A/127470: Polycomb-Associated Non-Coding RNAs.
MA555543 - JP 2018138019-A/127469: Polycomb-Associated Non-Coding RNAs.
MA555542 - JP 2018138019-A/127468: Polycomb-Associated Non-Coding RNAs.
MA555541 - JP 2018138019-A/127467: Polycomb-Associated Non-Coding RNAs.
MA555540 - JP 2018138019-A/127466: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A8I5KYV3, A0A8I5KYV3_HUMAN, NM_001375585, SMG7 , uc330rpe.1, uc330rpe.2
UCSC ID: ENST00000688051.1_3
RefSeq Accession: NM_001375584.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.