The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9H254
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AF324064 - Homo sapiens beta spectrin IV mRNA, complete cds. AF324063 - Homo sapiens non-erythrocytic beta-spectrin 4 (SPNB4) mRNA, complete cds. AF082075 - Homo sapiens beta4sigma1 spectrin mRNA, complete cds. AF311855 - Homo sapiens spectrin beta IV (SPTBN3) mRNA, complete cds, alternatively spliced. AY004227 - Homo sapiens betaIV spectrin isoform sigma4 mRNA, complete cds, alternatively spliced. AY004226 - Homo sapiens betaIV spectrin isoform sigma2 and betaIV spectrin isoform sigma3 bicistronic mRNA, complete cds, alternatively spliced. AB046862 - Homo sapiens mRNA for KIAA1642 protein, partial cds. JD107861 - Sequence 88885 from Patent EP1572962. JD443490 - Sequence 424514 from Patent EP1572962. JD218363 - Sequence 199387 from Patent EP1572962. AF311856 - Homo sapiens spectrin beta IV (SPTBN3) mRNA, complete cds, alternatively spliced. AK309418 - Homo sapiens cDNA, FLJ99459. AK308547 - Homo sapiens cDNA, FLJ98588. AL133093 - Homo sapiens mRNA; cDNA DKFZp434J0328 (from clone DKFZp434J0328); partial cds. LT220019 - Homo sapiens microRNA stbn4-miR1-3p. AK054915 - Homo sapiens cDNA FLJ30353 fis, clone BRACE2007663. JD419935 - Sequence 400959 from Patent EP1572962. JD498406 - Sequence 479430 from Patent EP1572962. JD534530 - Sequence 515554 from Patent EP1572962. JD078651 - Sequence 59675 from Patent EP1572962. JD051029 - Sequence 32053 from Patent EP1572962. JD131603 - Sequence 112627 from Patent EP1572962. JD413928 - Sequence 394952 from Patent EP1572962. JD145853 - Sequence 126877 from Patent EP1572962. JD288452 - Sequence 269476 from Patent EP1572962. JD321893 - Sequence 302917 from Patent EP1572962. JD195714 - Sequence 176738 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q9H254 (Reactome details) participates in the following event(s):
R-HSA-391868 Dephosphorylation of NCAM1 bound pFyn R-NUL-420388 Dephosphorylation of NCAM1 bound pFyn R-HSA-391865 Recruitment of FAK to NCAM1:Fyn in lipid rafts R-HSA-391871 Autophosphorylation of NCAM1 bound Fyn R-HSA-392751 L1 linked to actin cytoskeleton by ankyrin R-HSA-6807875 ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex R-NUL-420398 Autophosphorylation of NCAM1 bound Fyn R-HSA-391866 Phosphorylation of FAK by Src kinase R-HSA-392051 Recruitment of Grb2 to pFAK:NCAM1 R-HSA-392053 SOS binds Grb2 bound to pFAK:NCAM1 R-HSA-373739 Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 R-HSA-6807877 ARFGAPs stimulate ARF GTPase activity R-HSA-6809003 ERGIC-to-Golgi vesicles bind dynein:dynactin R-HSA-392054 NCAM1:pFAK:Grb2:Sos-mediated nucleotide exchange of Ras R-HSA-6809006 Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex R-HSA-6809011 cis-Golgi t-SNAREs bind YKT6 on tethered vesicle R-HSA-5672965 RAS GEFs promote RAS nucleotide exchange R-HSA-375165 NCAM signaling for neurite out-growth R-HSA-445095 Interaction between L1 and Ankyrins R-HSA-6807878 COPI-mediated anterograde transport R-HSA-422475 Axon guidance R-HSA-373760 L1CAM interactions R-HSA-199977 ER to Golgi Anterograde Transport R-HSA-1266738 Developmental Biology R-HSA-199991 Membrane Trafficking R-HSA-948021 Transport to the Golgi and subsequent modification R-HSA-5673001 RAF/MAP kinase cascade R-HSA-5653656 Vesicle-mediated transport R-HSA-446203 Asparagine N-linked glycosylation R-HSA-5684996 MAPK1/MAPK3 signaling R-HSA-597592 Post-translational protein modification R-HSA-5683057 MAPK family signaling cascades R-HSA-392499 Metabolism of proteins R-HSA-162582 Signal Transduction
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
