Human Gene STS (ENST00000674429.1_9) from GENCODE V47lift37
  Description: steroid sulfatase, transcript variant 4 (from RefSeq NM_001320752.2)
Gencode Transcript: ENST00000674429.1_9
Gencode Gene: ENSG00000101846.9_13
Transcript (Including UTRs)
   Position: hg19 chrX:7,065,753-7,272,682 Size: 206,930 Total Exon Count: 11 Strand: +
Coding Region
   Position: hg19 chrX:7,171,241-7,268,302 Size: 97,062 Coding Exon Count: 9 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:7,065,753-7,272,682)mRNA (may differ from genome)Protein (578 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsHGNC
MalacardsMGIOMIMPubMedUniProtKBWikipedia
BioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: STS
Diseases sorted by gene-association score: ichthyosis, x-linked* (1725), ichthyosis* (468), pre-descemet corneal dystrophy (18), ichthyosis vulgaris (16), smith-lemli-opitz syndrome (15), chondrodysplasia punctata syndrome (13), multiple sulfatase deficiency (13), alopecia, androgenetic, 1 (10), chondrodysplasia punctata, x-linked dominant (9), schneckenbecken dysplasia (8), kallmann syndrome (7), corneal dystrophy, thiel-behnke type (7), corneal granular dystrophy (7), metachromatic leukodystrophy (6), x-linked chondrodysplasia punctata (6), hypervitaminosis a (5), chandler syndrome (5), ichthyosis, congenital, autosomal recessive 1 (5), tyrosinemia, type ii (4), breast cancer (3), cryptorchidism (2), attention deficit-hyperactivity disorder (2), congenital ichthyosiform erythroderma (1), autosomal recessive congenital ichthyosis (1)
* = Manually curated disease association

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -227.40505-0.450 Picture PostScript Text
3' UTR -1142.804380-0.261 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
      
      

-  Descriptions from all associated GenBank mRNAs
  AM282551 - Homo sapiens partial mRNA for steroid sulfatase (STS gene), from mammary gland.
AM072429 - Homo sapiens partial mRNA for steroid sulfatase (STS gene), transcript 2.
AM072428 - Homo sapiens partial mRNA for steroid sulfatase (STS gene), transcript 1.
FM209047 - Homo sapiens partial mRNA for steroid sulfatase isozyme S (STS gene), from mammary gland.
AM282552 - Homo sapiens partial mRNA for steroid sulfatase (STS gene), from ovary.
M16505 - Human steroid sulfatase (STS) mRNA, complete cds.
J04964 - Human steroid sulfatase (microsomal), complete cds.
AK314034 - Homo sapiens cDNA, FLJ94694, highly similar to Homo sapiens steroid sulfatase (microsomal), arylsulfatase C,isozyme S (STS), mRNA.
BC075030 - Homo sapiens steroid sulfatase (microsomal), isozyme S, mRNA (cDNA clone MGC:104007 IMAGE:30915417), complete cds.
KJ896457 - Synthetic construct Homo sapiens clone ccsbBroadEn_05851 STS gene, encodes complete protein.
KR712134 - Synthetic construct Homo sapiens clone CCSBHm_00036029 STS (STS) mRNA, encodes complete protein.
KR712135 - Synthetic construct Homo sapiens clone CCSBHm_00036031 STS (STS) mRNA, encodes complete protein.
KR712136 - Synthetic construct Homo sapiens clone CCSBHm_00036037 STS (STS) mRNA, encodes complete protein.
HZ409571 - JP 2015528002-A/2168: CHIRAL CONTROL.
LG052905 - KR 1020150036642-A/2171: CHIRAL CONTROL.
FR773073 - Homo sapiens microRNA hsa-miR-4767-5p.
HZ481953 - JP 2015535430-A/2459: TERMINALLY MODIFIED RNA.
HZ791884 - JP 2016504050-A/3629: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
JC514616 - Sequence 4869 from Patent WO2014113089.
LF161908 - JP 2016513950-A/1974: Oligomers with improved off-target profile.
LP951964 - Sequence 470 from Patent WO2017157650.
LQ072204 - Sequence 2528 from Patent EP2964234.
LQ724955 - Sequence 588 from Patent WO2018096084.
DQ851172 - Homo sapiens steroid sulfatase mRNA, partial sequence, alternatively spliced.
MA645705 - JP 2017113010-A/3629: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
MA733589 - JP 2017140048-A/2459: TERMINALLY MODIFIED RNA.
MA405832 - WO 2018155427-A/606: A probe with reduced false positive binding, a method to desing the probe, and the use thereof.
MP042764 - Sequence 3 from Patent WO2018202723.
MA802758 - JP 2018183181-A/3629: SIGNAL-SENSOR POLYNUCLEOTIDES FOR THE ALTERATION OF CELLULAR PHENOTYPES.
LY648329 - KR 1020190009674-A/8: miR494 as a biomarker for parkinson's disease and diagnostic kit using thereof.
LY649612 - KR 1020190009675-A/8: miR1244 as a biomarker for parkinson's disease and diagnostic kit using thereof.
LY649621 - KR 1020190009676-A/8: miR6768 as a biomarker for parkinson's disease and diagnostic kit using thereof.
LY649630 - KR 1020190009677-A/8: miR4324 as a biomarker for parkinson's disease and diagnostic kit using thereof.
LY649639 - KR 1020190009678-A/8: miR4726 as a biomarker for parkinson's disease and diagnostic kit using thereof.
LY649648 - KR 1020190009679-A/8: miR501 as a biomarker for parkinson's disease and diagnostic kit using thereof.
LY663932 - KR 1020190009722-A/8: miR1226 as a biomarker for parkinson's disease and diagnostic kit using thereof.
LY663941 - KR 1020190009723-A/8: miR4767 as a biomarker for parkinson's disease and diagnostic kit using thereof.
LY663950 - KR 1020190009724-A/8: miR3064 as a biomarker for parkinson's disease and diagnostic kit using thereof.
DQ851171 - Homo sapiens steroid sulfatase mRNA, partial cds, alternatively spliced.
FM209048 - Homo sapiens partial mRNA for steroid sulfatase isozyme S (STS gene), from PC3 cell line.
AM282553 - Homo sapiens partial mRNA for steroid sulfatase (STS gene), from thyroid.
AM282554 - Homo sapiens partial mRNA for steroid sulfatase (STS gene), from peripheral blood.
M17591 - Human steroid sulfatase mRNA, partial cds.
JD378485 - Sequence 359509 from Patent EP1572962.
JD050914 - Sequence 31938 from Patent EP1572962.
JD364930 - Sequence 345954 from Patent EP1572962.
JD353510 - Sequence 334534 from Patent EP1572962.
JD262740 - Sequence 243764 from Patent EP1572962.
JD504031 - Sequence 485055 from Patent EP1572962.
JD445808 - Sequence 426832 from Patent EP1572962.
JD265683 - Sequence 246707 from Patent EP1572962.
JD175538 - Sequence 156562 from Patent EP1572962.
JD111328 - Sequence 92352 from Patent EP1572962.
JD566292 - Sequence 547316 from Patent EP1572962.
JD178838 - Sequence 159862 from Patent EP1572962.
JD122410 - Sequence 103434 from Patent EP1572962.
JD562803 - Sequence 543827 from Patent EP1572962.
JD093320 - Sequence 74344 from Patent EP1572962.
JD172276 - Sequence 153300 from Patent EP1572962.
JD187961 - Sequence 168985 from Patent EP1572962.
JD244331 - Sequence 225355 from Patent EP1572962.
JD114127 - Sequence 95151 from Patent EP1572962.
JD512396 - Sequence 493420 from Patent EP1572962.
JD348198 - Sequence 329222 from Patent EP1572962.
JD184800 - Sequence 165824 from Patent EP1572962.
JD210115 - Sequence 191139 from Patent EP1572962.
JD263648 - Sequence 244672 from Patent EP1572962.
JD045835 - Sequence 26859 from Patent EP1572962.
JD164816 - Sequence 145840 from Patent EP1572962.
JD248845 - Sequence 229869 from Patent EP1572962.
JD516706 - Sequence 497730 from Patent EP1572962.
JD166443 - Sequence 147467 from Patent EP1572962.
JD551835 - Sequence 532859 from Patent EP1572962.
JD267366 - Sequence 248390 from Patent EP1572962.
JD150278 - Sequence 131302 from Patent EP1572962.
JD063151 - Sequence 44175 from Patent EP1572962.
JD130430 - Sequence 111454 from Patent EP1572962.
JD281848 - Sequence 262872 from Patent EP1572962.
JD488536 - Sequence 469560 from Patent EP1572962.
JD494655 - Sequence 475679 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A590UJL0, A0A590UJL0_HUMAN, A0A6I8PRU4, NM_001320752, STS , uc329yhf.1, uc329yhf.2
UCSC ID: ENST00000674429.1_9
RefSeq Accession: NM_001320752.2

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.