The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6IBA2
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003677 DNA binding GO:0003678 DNA helicase activity GO:0003690 double-stranded DNA binding GO:0003697 single-stranded DNA binding GO:0003713 transcription coactivator activity GO:0033613 activating transcription factor binding GO:0042802 identical protein binding
Biological Process: GO:0006355 regulation of transcription, DNA-templated GO:0006366 transcription from RNA polymerase II promoter GO:0032508 DNA duplex unwinding GO:0045944 positive regulation of transcription from RNA polymerase II promoter GO:0051260 protein homooligomerization GO:0060395 SMAD protein signal transduction
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Sequence and Links to Tools and Databases 
Common Gene Haplotype Alleles 
