Human Gene TANC2 (ENST00000689528.1_4) from GENCODE V47lift37
  Description: tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2, transcript variant 1 (from RefSeq NM_001394998.1)
Gencode Transcript: ENST00000689528.1_4
Gencode Gene: ENSG00000170921.16_13
Transcript (Including UTRs)
   Position: hg19 chr17:61,043,596-61,505,064 Size: 461,469 Total Exon Count: 28 Strand: +
Coding Region
   Position: hg19 chr17:61,086,921-61,499,316 Size: 412,396 Coding Exon Count: 27 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
Microarray ExpressionRNA StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2024-08-22 23:36:26

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr17:61,043,596-61,505,064)mRNA (may differ from genome)Protein (2074 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsHGNC
MalacardsMGIPubMedUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: TANC2
Diseases sorted by gene-association score: oral hairy leukoplakia (9)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -308.10538-0.573 Picture PostScript Text
3' UTR -1743.105748-0.303 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
      
      

-  Descriptions from all associated GenBank mRNAs
  BC172364 - Synthetic construct Homo sapiens clone IMAGE:100069058, MGC:199069 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 (TANC2) mRNA, encodes complete protein.
BC144357 - Homo sapiens cDNA clone IMAGE:9052878, with apparent retained intron.
AB046856 - Homo sapiens mRNA for KIAA1636 protein, partial cds.
AK021886 - Homo sapiens cDNA FLJ11824 fis, clone HEMBA1006492.
AK001077 - Homo sapiens cDNA FLJ10215 fis, clone HEMBA1006737.
AJ278120 - Homo sapiens mRNA for putative ankyrin-repeat containing protein (ORF1).
CR936685 - Homo sapiens mRNA; cDNA DKFZp686C08243 (from clone DKFZp686C08243).
JD256272 - Sequence 237296 from Patent EP1572962.
AB032974 - Homo sapiens mRNA for KIAA1148 protein, partial cds.
JD360473 - Sequence 341497 from Patent EP1572962.
JD303711 - Sequence 284735 from Patent EP1572962.
JD551237 - Sequence 532261 from Patent EP1572962.
JD367537 - Sequence 348561 from Patent EP1572962.
JD359354 - Sequence 340378 from Patent EP1572962.
JD298298 - Sequence 279322 from Patent EP1572962.
JD519060 - Sequence 500084 from Patent EP1572962.
JD230331 - Sequence 211355 from Patent EP1572962.
JD191779 - Sequence 172803 from Patent EP1572962.
JD383668 - Sequence 364692 from Patent EP1572962.
JD524982 - Sequence 506006 from Patent EP1572962.
JD433142 - Sequence 414166 from Patent EP1572962.
JD334657 - Sequence 315681 from Patent EP1572962.
JD261381 - Sequence 242405 from Patent EP1572962.
JD287817 - Sequence 268841 from Patent EP1572962.
JD564936 - Sequence 545960 from Patent EP1572962.
JD194190 - Sequence 175214 from Patent EP1572962.
JD307354 - Sequence 288378 from Patent EP1572962.
JD082161 - Sequence 63185 from Patent EP1572962.
JD170523 - Sequence 151547 from Patent EP1572962.
JD098595 - Sequence 79619 from Patent EP1572962.
JD182732 - Sequence 163756 from Patent EP1572962.
JD322192 - Sequence 303216 from Patent EP1572962.
JD301671 - Sequence 282695 from Patent EP1572962.
JD040185 - Sequence 21209 from Patent EP1572962.
JD339420 - Sequence 320444 from Patent EP1572962.
JD450086 - Sequence 431110 from Patent EP1572962.
JD273818 - Sequence 254842 from Patent EP1572962.
JD406525 - Sequence 387549 from Patent EP1572962.
JD418739 - Sequence 399763 from Patent EP1572962.
JD336728 - Sequence 317752 from Patent EP1572962.
JD193246 - Sequence 174270 from Patent EP1572962.
JD285670 - Sequence 266694 from Patent EP1572962.
JD458804 - Sequence 439828 from Patent EP1572962.
JD184632 - Sequence 165656 from Patent EP1572962.
JD305448 - Sequence 286472 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A8I5KXR5, A0A8I5KXR5_HUMAN, NM_001394998, TANC2 , uc330tnb.1, uc330tnb.2
UCSC ID: ENST00000689528.1_4
RefSeq Accession: NM_001394998.1

-  Gene Model Information
  Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.