ID:TM102_HUMAN DESCRIPTION: RecName: Full=Transmembrane protein 102; AltName: Full=Common beta-chain associated protein; Short=CBAP; FUNCTION: Selectively involved in CSF2 deprivation-induced apoptosis via a mitochondria-dependent pathway. SUBUNIT: Interacts with CSF2RB; this interaction occurs preferentially in the absence of CSF2. SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein. Note=Although it is found at the cell surface, the majority of the molecules seems to be located in intracellular compartments.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q8N9M5
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006915 apoptotic process GO:0007165 signal transduction GO:0010820 positive regulation of T cell chemotaxis GO:0034097 response to cytokine GO:0042981 regulation of apoptotic process GO:0045785 positive regulation of cell adhesion GO:0050730 regulation of peptidyl-tyrosine phosphorylation GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:2000406 positive regulation of T cell migration