Human Gene TMEM187 (ENST00000369982.5_4) from GENCODE V47lift37
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Sequence and Links to Tools and Databases
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Comments and Description Text from UniProtKB
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ID: TM187_HUMAN
DESCRIPTION: RecName: Full=Transmembrane protein 187; AltName: Full=Protein ITBA1;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). TISSUE SPECIFICITY: Ubiquitous.
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Primer design for this transcript
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Comparative Toxicogenomics Database (CTD)
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The following chemicals interact with this gene
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Common Gene Haplotype Alleles
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Press "+" in the title bar above to open this section.
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
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The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
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Protein Domain and Structure Information
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Pfam Domains: PF15100 - TMEM187 protein family
SCOP Domains: 53474 - alpha/beta-Hydrolases
ModBase Predicted Comparative 3D Structure on Q14656
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
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Orthologous Genes in Other Species
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Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse | Rat | Zebrafish | D. melanogaster | C. elegans | S. cerevisiae |
No ortholog | No ortholog | No ortholog | No ortholog | No ortholog | No ortholog |
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Gene Ontology (GO) Annotations with Structured Vocabulary
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Descriptions from all associated GenBank mRNAs
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DQ655925 - Homo sapiens clone UGL3c12, mRNA sequence. AK314938 - Homo sapiens cDNA, FLJ95849. X92475 - H.sapiens mRNA for ITBA1 protein. BC008203 - Homo sapiens transmembrane protein 187, mRNA (cDNA clone MGC:17711 IMAGE:3868838), complete cds. BC017026 - Homo sapiens transmembrane protein 187, mRNA (cDNA clone MGC:9043 IMAGE:3847234), complete cds. JD083740 - Sequence 64764 from Patent EP1572962. JD190255 - Sequence 171279 from Patent EP1572962. JD047228 - Sequence 28252 from Patent EP1572962. JD482830 - Sequence 463854 from Patent EP1572962. JD414330 - Sequence 395354 from Patent EP1572962. JD513840 - Sequence 494864 from Patent EP1572962. JD491378 - Sequence 472402 from Patent EP1572962. AM393452 - Synthetic construct Homo sapiens clone IMAGE:100002056 for hypothetical protein (CXorf12 gene). AB528750 - Synthetic construct DNA, clone: pF1KE0133, Homo sapiens TMEM187 gene for transmembrane protein 187, without stop codon, in Flexi system. CR457047 - Homo sapiens full open reading frame cDNA clone RZPDo834A0615D for gene CXorf12, chromosome X open reading frame 12; complete cds, incl. stopcodon. CU677803 - Synthetic construct Homo sapiens gateway clone IMAGE:100018654 5' read TMEM187 mRNA. KJ892485 - Synthetic construct Homo sapiens clone ccsbBroadEn_01879 TMEM187 gene, encodes complete protein. JD128260 - Sequence 109284 from Patent EP1572962. JD557232 - Sequence 538256 from Patent EP1572962. JD289356 - Sequence 270380 from Patent EP1572962.
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Other Names for This Gene
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Alternate Gene Symbols: B2RC47, CXorf12, DXS9878E, ENST00000369982.1, ENST00000369982.2, ENST00000369982.3, ENST00000369982.4, ITBA1, NM_003492, Q14656, Q6IAV7, TM187_HUMAN, uc318hzu.1, uc318hzu.2 UCSC ID: ENST00000369982.5_4 RefSeq Accession: NM_003492.3
Protein: Q14656
(aka TM187_HUMAN)
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Gene Model Information
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for a detailed description of the fields of the table above.
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.
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