Human Gene TMEM241 (ENST00000383233.8_8) from GENCODE V47lift37
Description: transmembrane protein 241, transcript variant 9 (from RefSeq NR_148385.2)
Gencode Transcript: ENST00000383233.8_8
Gencode Gene: ENSG00000134490.14_11
Transcript (Including UTRs)
Position: hg19 chr18:20,875,977-21,017,925 Size: 141,949 Total Exon Count: 15 Strand: -
Coding Region
Position: hg19 chr18:20,877,971-21,017,816 Size: 139,846 Coding Exon Count: 15
Data last updated at UCSC: 2024-08-22 23:36:26
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: TM241_HUMAN
DESCRIPTION: RecName: Full=Transmembrane protein 241;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).SIMILARITY: Belongs to the TMEM241 family.
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
SCOP Domains: 103481 - Multidrug resistance efflux transporter EmrE
ModBase Predicted Comparative 3D Structure on Q24JQ0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0005338 nucleotide-sugar transmembrane transporter activity
Biological Process: GO:1990570 GDP-mannose transmembrane transport
Cellular Component: GO:0016020 membrane
GO:0016021 integral component of membrane
Descriptions from all associated GenBank mRNAs
AK294916 - Homo sapiens cDNA FLJ60518 complete cds.AK123623 - Homo sapiens cDNA FLJ41629 fis, clone DFNES2010502.AK126247 - Homo sapiens cDNA FLJ44259 fis, clone TLIVE2000023.BC114510 - Homo sapiens chromosome 18 open reading frame 45, mRNA (cDNA clone MGC:138577 IMAGE:40023922), complete cds.BC114561 - Homo sapiens chromosome 18 open reading frame 45, mRNA (cDNA clone MGC:138578 IMAGE:40023923), complete cds.KJ895076 - Synthetic construct Homo sapiens clone ccsbBroadEn_04470 TMEM241 gene, encodes complete protein.AB253738 - Homo sapiens hVVT mRNA for putative vertebrate vrg4-like nucleotide-sugar transporter variant1, complete cds.AB253739 - Homo sapiens hVVT mRNA for putative vertebrate vrg4-like nucleotide-sugar transporter truncated variant2, complete cds.AK303553 - Homo sapiens cDNA FLJ57467 complete cds.BC006280 - Homo sapiens chromosome 18 open reading frame 45, mRNA (cDNA clone IMAGE:3957352).BC082984 - Homo sapiens chromosome 18 open reading frame 45, mRNA (cDNA clone IMAGE:6729630).BC054507 - Homo sapiens chromosome 18 open reading frame 45, mRNA (cDNA clone IMAGE:3846642), partial cds.JD554836 - Sequence 535860 from Patent EP1572962.JD416064 - Sequence 397088 from Patent EP1572962.JD049249 - Sequence 30273 from Patent EP1572962.JD049254 - Sequence 30278 from Patent EP1572962.JD301561 - Sequence 282585 from Patent EP1572962.JD117000 - Sequence 98024 from Patent EP1572962.JD360326 - Sequence 341350 from Patent EP1572962.JD292783 - Sequence 273807 from Patent EP1572962.JD177389 - Sequence 158413 from Patent EP1572962.JD446976 - Sequence 428000 from Patent EP1572962.JD511427 - Sequence 492451 from Patent EP1572962.JD286556 - Sequence 267580 from Patent EP1572962.JD533778 - Sequence 514802 from Patent EP1572962.JD167658 - Sequence 148682 from Patent EP1572962.JD481338 - Sequence 462362 from Patent EP1572962.JD103823 - Sequence 84847 from Patent EP1572962.JD038753 - Sequence 19777 from Patent EP1572962.JD180842 - Sequence 161866 from Patent EP1572962.JD520784 - Sequence 501808 from Patent EP1572962.JD094406 - Sequence 75430 from Patent EP1572962.JD459732 - Sequence 440756 from Patent EP1572962.JD476521 - Sequence 457545 from Patent EP1572962.JD560632 - Sequence 541656 from Patent EP1572962.JD245942 - Sequence 226966 from Patent EP1572962.JD448595 - Sequence 429619 from Patent EP1572962.JD299482 - Sequence 280506 from Patent EP1572962.JD333194 - Sequence 314218 from Patent EP1572962.JD566678 - Sequence 547702 from Patent EP1572962.JD361377 - Sequence 342401 from Patent EP1572962.JD241971 - Sequence 222995 from Patent EP1572962.JD523240 - Sequence 504264 from Patent EP1572962.JD417989 - Sequence 399013 from Patent EP1572962.JD465138 - Sequence 446162 from Patent EP1572962.JD459574 - Sequence 440598 from Patent EP1572962.JD459573 - Sequence 440597 from Patent EP1572962.JD523239 - Sequence 504263 from Patent EP1572962.JD417988 - Sequence 399012 from Patent EP1572962.JD524146 - Sequence 505170 from Patent EP1572962.JD378386 - Sequence 359410 from Patent EP1572962.JD159823 - Sequence 140847 from Patent EP1572962.JD505084 - Sequence 486108 from Patent EP1572962.JD065588 - Sequence 46612 from Patent EP1572962.JD426377 - Sequence 407401 from Patent EP1572962.JD527139 - Sequence 508163 from Patent EP1572962.JD167144 - Sequence 148168 from Patent EP1572962.JD246278 - Sequence 227302 from Patent EP1572962.JD375752 - Sequence 356776 from Patent EP1572962.AK314123 - Homo sapiens cDNA, FLJ94820.KJ903509 - Synthetic construct Homo sapiens clone ccsbBroadEn_12903 TMEM241 gene, encodes complete protein.JD047144 - Sequence 28168 from Patent EP1572962.JD181852 - Sequence 162876 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: C18orf45, ENST00000383233.1, ENST00000383233.2, ENST00000383233.3, ENST00000383233.4, ENST00000383233.5, ENST00000383233.6, ENST00000383233.7, I0J130, NR_148385, Q24JQ0, Q6ZTS7, Q6ZW41, TM241_HUMAN, uc318rdj.1, uc318rdj.2UCSC ID: ENST00000383233.8_8RefSeq Accession: NM_032933.6
Protein: Q24JQ0
(aka TM241_HUMAN)
Gene Model Information
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for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.