Human Gene TMEM60 (ENST00000257663.4_7) from GENCODE V47lift37
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 Sequence and Links to Tools and Databases
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Comments and Description Text from UniProtKB
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ID: TMM60_HUMAN
DESCRIPTION: RecName: Full=Transmembrane protein 60;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential). SEQUENCE CAUTION: Sequence=AAH65930.1; Type=Erroneous initiation;
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 Primer design for this transcript
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 Comparative Toxicogenomics Database (CTD)
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 Common Gene Haplotype Alleles
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Press "+" in the title bar above to open this section.
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 RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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 Microarray Expression Data
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 mRNA Secondary Structure of 3' and 5' UTRs
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The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
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 Protein Domain and Structure Information
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InterPro Domains: Graphical view of domain structure IPR019396 - TM_Fragile-X-F-assoc
Pfam Domains: PF10269 - Transmembrane Fragile-X-F protein
ModBase Predicted Comparative 3D Structure on Q9H2L4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
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 Orthologous Genes in Other Species
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Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
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 Gene Ontology (GO) Annotations with Structured Vocabulary
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 Descriptions from all associated GenBank mRNAs
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BC012192 - Homo sapiens cDNA clone IMAGE:4556087, containing frame-shift errors. BC065930 - Homo sapiens transmembrane protein 60, mRNA (cDNA clone MGC:74482 IMAGE:6146561), complete cds. AF260336 - Homo sapiens DC32 mRNA, complete cds. JD448099 - Sequence 429123 from Patent EP1572962. JD287787 - Sequence 268811 from Patent EP1572962. JD160675 - Sequence 141699 from Patent EP1572962. JD530878 - Sequence 511902 from Patent EP1572962. HQ257945 - Synthetic construct Homo sapiens clone IMAGE:100072254 transmembrane protein 60 (TMEM60) gene, encodes complete protein. KJ903512 - Synthetic construct Homo sapiens clone ccsbBroadEn_12906 TMEM60 gene, encodes complete protein. AB464317 - Synthetic construct DNA, clone: pF1KB7086, Homo sapiens TMEM60 gene for transmembrane protein 60, without stop codon, in Flexi system. JD086897 - Sequence 67921 from Patent EP1572962.
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 Other Names for This Gene
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Alternate Gene Symbols: A4D1C3, C7orf35, DC32, ENST00000257663.1, ENST00000257663.2, ENST00000257663.3, NM_032936, Q86UM0, Q9H2L4, TMM60_HUMAN, uc317fza.1, uc317fza.2 UCSC ID: ENST00000257663.4_7 RefSeq Accession: NM_032936.4
Protein: Q9H2L4
(aka TMM60_HUMAN)
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 Gene Model Information
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Click here
for a detailed description of the fields of the table above.
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 Methods, Credits, and Use Restrictions
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Click here
for details on how this gene model was made and data restrictions if any.
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